From the Guidelines
Lipoflavinoid supplementation is not recommended for managing tinnitus due to limited scientific evidence supporting its effectiveness. This over-the-counter supplement contains vitamins (primarily B vitamins) and bioflavonoids derived from lemon, and is marketed specifically for ear health and tinnitus relief. The typical recommended dosage is two capsules three times daily with meals, though this may vary by manufacturer. While some users report subjective improvement in their tinnitus symptoms, clinical research has not conclusively demonstrated its efficacy 1.
Tinnitus Management Strategies
Other tinnitus management strategies with stronger evidence include:
- Sound therapy
- Cognitive behavioral therapy (CBT) 1
- Addressing underlying conditions like hearing loss
Important Considerations
Patients should maintain realistic expectations, as tinnitus is complex and often requires a multifaceted approach. Before starting any supplements, individuals should consult with their healthcare provider, especially if taking other medications, as interactions are possible.
Clinical Guidelines
The American Academy of Otolaryngology-Head and Neck Surgery recommends against the use of dietary supplements, including lipoflavinoid, for treating patients with persistent, bothersome tinnitus 1. Instead, clinicians should recommend evidence-based treatments, such as CBT and sound therapy, to improve symptoms and quality of life for tinnitus sufferers.
From the Research
Lipoflavinoid Supplementation in Tinnitus Management
- Lipoflavinoid supplementation has been studied as a potential treatment for tinnitus, with mixed results 2, 3.
- A survey of 1,788 subjects found that 19.0% of those taking lipoflavonoid supplements reported an improvement in their tinnitus, while 10.3% reported a worsening of symptoms 2.
- A randomized controlled trial of 40 participants found no significant difference in tinnitus symptoms between those taking manganese and Lipoflavonoid Plus(®) and those taking Lipoflavonoid Plus(®) only 3.
- The effectiveness of lipoflavinoid supplementation in managing tinnitus is not well established, and more research is needed to fully understand its potential benefits and limitations.
Comparison to Other Treatments
- Cognitive behavioral therapy (CBT) has been shown to be effective in improving quality of life and reducing depression in patients with tinnitus 4, 5.
- Sound therapy, including the use of hearing aids and maskers, has also been studied as a potential treatment for tinnitus, but the evidence is limited and inconclusive 6.
- Lipoflavinoid supplementation may be more effective for certain aspects of tinnitus, such as sleep and emotional reactions, but the evidence is not strong enough to support its use as a primary treatment 2.
Potential Benefits and Risks
- Lipoflavinoid supplementation may have a positive effect on sleep and emotional reactions in some patients with tinnitus 2.
- However, the use of dietary supplements to treat tinnitus is not recommended due to the lack of strong evidence and the potential for adverse effects 2.
- Patients considering lipoflavinoid supplementation should consult with a healthcare professional to discuss the potential benefits and risks and to determine the best course of treatment for their individual needs.