What are the treatment options for male genitalia issues?

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Last updated: July 5, 2025View editorial policy

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From the Guidelines

Treatment options for male genitalia issues should prioritize the specific condition, with phimosis being treated with topical steroid creams or surgical circumcision if conservative measures fail, as recommended by the British Association of Dermatologists guidelines for the management of lichen sclerosus 2018 1. For erectile dysfunction, first-line treatments include oral medications like sildenafil (Viagra) 50-100mg, tadalafil (Cialis) 5-20mg, or vardenafil (Levitra) 10-20mg taken before sexual activity, as suggested by the American Urological Association guideline on erectile dysfunction 1. Some key considerations for male genitalia issues include:

  • Phimosis treatment with topical steroids or circumcision if necessary, with a recommendation for referral to an experienced urologist for circumcision if medical treatment fails 1
  • Erectile dysfunction treatment with PDE5 inhibitors, vacuum erection devices, penile injections, or surgical penile implants, depending on the severity of the condition 1
  • Premature ejaculation treatment with topical anesthetics, SSRIs, or behavioral techniques like the squeeze or stop-start methods
  • Testicular pain or inflammation treatment with antibiotics, anti-inflammatory medications, or supportive measures like scrotal support and ice packs
  • Peyronie's disease treatment with oral medications like pentoxifylline or collagenase clostridium histolyticum injections for moderate cases, while surgical correction may be needed for severe curvature It's essential to consult a healthcare provider for proper diagnosis and personalized treatment plans for any genital issue, considering the latest guidelines and evidence-based recommendations, such as those from the European Association of Urology-American Society of Clinical Oncology collaborative guideline on penile cancer: 2023 update 1.

From the Research

Male Genitalia Issues

  • Male genitalia issues can be caused by various factors, including bacterial infections, trauma, and congenital conditions.
  • Treatment options for male genitalia issues vary depending on the underlying cause and severity of the condition.

Bacterial Infections

  • Bacterial infections of the male genital tract, such as urethritis, epididymitis, and prostatitis, can be caused by sexually transmissible bacteria like Chlamydia trachomatis and Neisseria gonorrhoeae 2.
  • Treatment for bacterial infections typically involves antibiotics, such as fluoroquinolones or azalides, which have been shown to be effective and easy to use 2, 3.
  • However, the emergence of resistant strains to these agents is a concern, and patient compliance with treatment is crucial 2.

Phimosis and Other Conditions

  • Phimosis, a condition where the foreskin cannot be retracted, can be treated with topical steroid therapy, which has been shown to be effective in 67%-95% of cases 4.
  • Other conditions, such as epididymitis and orchitis, can be treated with antibiotics and supportive care 3.
  • Surgical intervention may be necessary for certain conditions, such as webbed penis and penile curvature, and can improve genital satisfaction in male adolescents 5.

Emergency Room Setting

  • In the emergency room setting, male external genital diseases can be evaluated and treated, including conditions such as penile and scrotal trauma, Fournier's gangrene, and the "acute" scrotum 6.
  • Practical advice regarding diagnosis and treatment is essential for emergency physicians to provide appropriate care for these conditions.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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