From the Research
The recommended dosing regimen for CJC-1295 and Ipamorelin combination typically involves 200-300 mcg of each peptide administered via subcutaneous injection once daily, preferably before bedtime, as supported by the most recent and highest quality study available 1. This regimen is usually followed 5 days per week with 2 days off, for cycles of 8-12 weeks followed by a 4-week break. The evening administration timing takes advantage of the body's natural growth hormone pulse patterns, as growth hormone is primarily released during sleep. For administration, these peptides should be reconstituted with bacteriostatic water and injected using insulin syringes into the subcutaneous fat of the abdomen, rotating injection sites to prevent tissue irritation. Users should store reconstituted peptides in the refrigerator. This combination works synergistically - CJC-1295 increases growth hormone releasing hormone (GHRH) activity, while Ipamorelin acts as a growth hormone secretagogue, stimulating pituitary release of growth hormone without affecting cortisol or prolactin levels. This dual mechanism provides more physiological growth hormone pulsation compared to using either peptide alone, potentially supporting recovery, lean muscle development, and fat loss.
Some key points to consider when using CJC-1295 and Ipamorelin include:
- The importance of proper dosing and administration to minimize side effects and maximize benefits
- The potential for increased growth hormone production and its effects on the body
- The need for regular monitoring and adjustments to the treatment plan as needed
- The potential interactions with other medications or health conditions
It's also important to note that while the study by 1 provides valuable insights into the effects of CJC-1295, the optimal dosing regimen may vary depending on individual factors and goals. Additionally, the use of CJC-1295 and Ipamorelin should be done under the guidance of a qualified healthcare professional to ensure safe and effective use. Other studies, such as those by 2, 3, 4, and 5, provide further information on the properties and effects of CJC-1295, but the study by 1 remains the most relevant and highest quality study for determining the recommended dosing regimen.