Is a HIDA (Hepatobiliary Iminodiacetic Acid) scan necessary before scheduled surgery for cholelithiasis?

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Last updated: July 6, 2025View editorial policy

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From the Guidelines

A HIDA scan is generally not necessary before scheduled surgery for cholelithiasis. For most patients with symptomatic gallstones who are planning to undergo cholecystectomy, the standard preoperative evaluation typically includes an ultrasound to confirm the presence of gallstones, routine blood work, and possibly liver function tests, such as gamma-glutamyl transpeptidase (GGT) which has been shown to have a sensitivity of 80.6% and a specificity of 75.3% in diagnosing common bile duct stones (CBDS) 1. A HIDA scan is a specialized nuclear medicine test that evaluates gallbladder function and bile duct patency, but it is not routinely required before gallstone surgery. This test is more commonly used in specific situations, such as when there is uncertainty about the diagnosis, when biliary dyskinesia is suspected, or when there are concerns about bile duct obstruction that cannot be resolved with ultrasound or other imaging. Some key points to consider include:

  • The incidence of CBDS is relatively low, ranging from 10% to 20% of gallstone cases 1
  • The presence of gallstones on ultrasound, combined with typical symptoms like biliary colic, is usually sufficient to establish the need for surgery
  • During cholecystectomy, surgeons can perform an intraoperative cholangiogram if there are concerns about common bile duct stones or anatomy, making preoperative HIDA scans unnecessary in most cases
  • Liver function tests, such as GGT, can be useful in identifying patients with a high likelihood of CBDS, who may benefit from further diagnostic tests and removal of CBDS 1

From the Research

HIDA Scan Necessity for Cholelithiasis Surgery

  • The provided studies do not directly address whether a HIDA scan is necessary before scheduled surgery for cholelithiasis 2, 3, 4, 5, 6.
  • However, studies suggest that HIDA scans are useful in diagnosing acute cholecystitis, with high sensitivity rates 4, 5, 6.
  • In cases where acute cholecystitis is suspected, a HIDA scan may be beneficial in confirming the diagnosis 5, 6.
  • Ultrasonography is also commonly used to diagnose cholelithiasis, but it may not provide information on the status of the cystic duct, which is essential for diagnosing acute cholecystitis 4.
  • The decision to perform a HIDA scan before surgery for cholelithiasis may depend on the individual patient's circumstances and the surgeon's preference 2, 3.

Diagnostic Modalities for Cholelithiasis

  • Ultrasonography and HIDA scans are both used to diagnose cholelithiasis and acute cholecystitis 4, 5, 6.
  • HIDA scans have been shown to be more sensitive than ultrasonography in diagnosing acute cholecystitis 6.
  • The combination of ultrasonography and HIDA scans may provide the most accurate diagnosis 6.
  • Other diagnostic modalities, such as endoscopic ultrasound, may also be useful in certain cases 3.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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