From the Guidelines
Hemp protein can be a suitable option for some patients with Chronic Kidney Disease (CKD), but it is not universally "safer" for all CKD patients, and its use should be individualized based on the patient's specific needs and health status, as recommended by the most recent guidelines 1. For individuals with CKD who need to limit protein intake, hemp protein offers several potential advantages, including providing a complete protein source containing all essential amino acids while typically delivering less protein per serving than animal proteins, which may help with protein restriction goals.
- Hemp protein is naturally free of phosphorus additives that are common in processed foods and can be problematic for CKD patients who need to limit phosphorus intake.
- Hemp seeds contain beneficial omega-3 fatty acids that may help reduce inflammation, a common concern in kidney disease. However, patients with CKD should always consult their nephrologist or renal dietitian before adding hemp protein to their diet, as individual protein needs vary based on CKD stage, dialysis status, and other health factors.
- The appropriate amount would need to be calculated as part of the patient's total daily protein allowance, which typically ranges from 0.6-1.2 g/kg of body weight depending on CKD stage and treatment, with a recommended daily allowance of 0.8 g/kg body weight per day for people with nondialysis-dependent CKD 1.
- Patients should also be aware that hemp protein contains potassium and phosphorus, which may need to be restricted in advanced CKD, so these levels should be monitored through regular blood work. The most recent guidelines suggest that dietary protein intake should be approximately 0.8 g/kg body weight per day for people with nondialysis-dependent CKD, and higher levels of dietary protein intake should be avoided as they have been associated with increased albuminuria, more rapid kidney function loss, and CVD mortality 1.
From the Research
Safety of Hemp Protein for CKD Patients
- The safety of hemp protein for patients with Chronic Kidney Disease (CKD) is a topic of interest, with some studies suggesting that plant-based proteins may be beneficial for CKD patients 2, 3.
- A systematic review of clinical trials found that plant-based protein interventions may preserve kidney function and reduce CKD-mineral bone disorder complications, although the evidence is limited and inconclusive 2.
- Another study found that plant-based proteins are sufficient in meeting both quantity and quality requirements for CKD patients, and may even have pleiotropic effects that favor their use in CKD patients 3.
Comparison of Plant-Based and Animal-Based Proteins
- Some studies have compared the effects of plant-based and animal-based proteins on CKD patients, with mixed results 4, 5, 6.
- A cross-sectional study found that higher plant protein intake was associated with lower fibroblast growth factor 23 and higher serum bicarbonate levels in CKD patients 5.
- A systematic review and meta-analysis found that plant proteins may reduce inflammation markers among adults with CKD, although the evidence is limited and caution is needed when interpreting the results 6.
Key Findings
- Plant-based proteins, including hemp protein, may be a safe and beneficial option for CKD patients 2, 3.
- More research is needed to fully understand the effects of hemp protein on CKD patients, including its impact on kidney function, inflammation markers, and overall health outcomes 2, 4, 6.
- CKD patients should consult with their healthcare provider or a registered dietitian to determine the best protein sources for their individual needs 3.