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Differential Diagnosis for 79-year-old with Sudden Onset Painful Swelling

  • Single most likely diagnosis:
    • Temporomandibular joint (TMJ) disorder or temporomandibular dysfunction: The symptoms of painful swelling, difficulty opening the mouth, and increased pain on bending are highly suggestive of a TMJ issue, possibly exacerbated by an acute injury or condition such as a dislocated jaw or TMJ inflammation.
  • Other Likely diagnoses:
    • Dental abscess or infection: Given the location and symptoms, an abscess or infection related to a tooth could cause swelling, pain, and difficulty opening the mouth.
    • Parotid gland infection or inflammation: Inflammation of the parotid gland (parotitis) could cause swelling and pain in the area described, especially if it's related to a bacterial or viral infection.
    • Masticatory space infection: An infection in the masticatory space, which includes muscles of mastication, could lead to swelling, pain, and difficulty moving the jaw.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.):
    • Angioedema: Although less common, angioedema could cause sudden swelling and potentially life-threatening airway obstruction if not promptly treated.
    • Ludwig's angina: A severe infection of the submandibular space that can cause swelling, pain, and difficulty opening the mouth, with potential for airway compromise.
    • Temporal arteritis: Inflammation of the temporal arteries could cause jaw claudication (pain when chewing) and is a medical emergency due to the risk of blindness if not treated promptly.
  • Rare diagnoses:
    • Salivary gland tumor: Although rare, a tumor of the salivary gland could cause a painful swelling, especially if it becomes infected or is large enough to cause mechanical symptoms.
    • Osteonecrosis of the jaw: More commonly associated with long-term bisphosphonate use, this condition could cause jaw pain and swelling, especially in the context of recent dental procedures.
    • Actinomycosis: A rare bacterial infection that can cause chronic swelling and pain, often related to dental procedures or poor dental hygiene.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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