What is the recommended dose of minoxidil (2% or 5% solution) for treating male pattern baldness in men?

From the Guidelines

The recommended dose of minoxidil for treating male pattern baldness in men is 1 mL of 5% solution applied twice daily to the affected areas of the scalp. This recommendation is based on the most recent and highest quality study available, which suggests that the 5% solution is more effective than the 2% formulation 1. The medication should be applied to a dry scalp, and users should wash their hands thoroughly after application. Results typically begin to appear after 4 months of consistent use, with maximum benefits seen around 12 months. Treatment must be continued indefinitely to maintain results, as hair loss will resume within 3-4 months if minoxidil is discontinued.

Key Points to Consider

• Minoxidil works by prolonging the growth phase of hair follicles and increasing blood flow to the scalp, which helps stimulate hair growth.
• Side effects may include scalp irritation, unwanted hair growth in adjacent areas, and initial shedding during the first few weeks of treatment.
• If severe irritation occurs, users should discontinue use and consult a healthcare provider.
• Some studies have shown that combining minoxidil with other treatments, such as platelet-rich plasma (PRP) therapy, may be more effective than using minoxidil alone 1.

Important Considerations

• The effectiveness of minoxidil can vary depending on individual factors, such as the severity of hair loss and the presence of other medical conditions.
• Users should be aware that minoxidil is a long-term treatment, and results may take several months to appear.
• Regular follow-up with a healthcare provider is recommended to monitor progress and adjust treatment as needed.

From the FDA Drug Label

apply one mL with dropper 2 times a day directly onto the scalp in the hair loss area using more or more often will not improve results minoxidil topical solution 5% for men provided more hair regrowth than minoxidil topical solution 2% For some men, you may need to use this product for at least 4 months before you see results.

The recommended dose of minoxidil for treating male pattern baldness in men is 2 times a day, with one mL applied directly to the scalp using a dropper. The 5% solution is more effective than the 2% solution for men. It is essential to use the product consistently and as directed to see results, which may take at least 4 months 2.

From the Research

Minoxidil Dose for Men

The recommended dose of minoxidil for treating male pattern baldness in men is available in two strengths: 2% and 5% solution.

• The 2% minoxidil solution is applied twice daily, as seen in a study where men with male pattern baldness were treated with either twice-daily 2% topical minoxidil for 12 months or 3% topical minoxidil for 8 to 12 months 3.
• Another study compared the efficacy of 2% and 3% minoxidil solutions, and found significant regrowth of nonvellus hairs in patients using both solutions 4.
• The 5% minoxidil solution is also available, and has been shown to be effective in treating male pattern baldness, as mentioned in a study that discussed new treatments for androgenetic alopecia, including 5% minoxidil and 1 mg finasteride 5.
• It's worth noting that the efficacy of minoxidil can vary from person to person, and some studies have found that it may have a prophylactic effect, but not significantly affect the long-term course of male pattern baldness 6.

Comparison of 2% and 5% Minoxidil Solutions

• A study found that 5% minoxidil foam provides an additional option for women with female pattern hair loss, and established noninferiority of the 5% foam formulation compared to twice daily 2% minoxidil solution 7.
• However, the study did not specifically compare the efficacy of 2% and 5% minoxidil solutions in men.
• Another study found that men who continued with twice-daily application of topical minoxidil had a greater mean increase in nonvellus hair count compared to those who changed to once-daily application 3.

Treatment Options

• Minoxidil is available over-the-counter in 2% and 5% solutions, and can be used in conjunction with other treatments, such as finasteride, for optimal results 5.
• It's essential to follow the recommended dosage and application instructions for minoxidil to achieve the best possible outcomes.