What are the symptoms of pleomorphic adenoma (benign salivary gland tumor)?

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From the Research

Pleomorphic adenomas typically present as a painless, slow-growing lump or swelling, most commonly in the parotid gland, and are generally firm, mobile, and non-tender when touched, as reported in the most recent study 1. The symptoms of pleomorphic adenoma, a benign salivary gland tumor, can vary depending on the size and location of the tumor.

  • Common symptoms include:
    • A painless, slow-growing lump or swelling in the parotid gland, which is the largest salivary gland located in front of the ear 2, 1
    • Facial asymmetry as the mass enlarges
    • Difficulty chewing, speaking, or swallowing if the tumor compresses surrounding structures
    • Rarely, facial nerve weakness or numbness if the tumor presses on nearby nerves
  • Uncommon symptoms include:
    • Pain, which may suggest infection or malignant transformation 3, 4
    • Systemic manifestations like fever or weight loss, which are typically absent in pleomorphic adenomas 2, 1 The diagnosis of pleomorphic adenoma can be made using fine-needle aspiration, ultrasonography, and computed tomography scan, and the treatment typically involves surgical removal of the tumor to prevent recurrence and malignant transformation 5, 1. The most important consideration in the management of pleomorphic adenoma is early detection and surgical removal to minimize the risk of malignant transformation and recurrence, as emphasized in the most recent and highest quality study 1.

References

Research

Clinico-histopathological review of 255 patients who underwent parotidectomy for pleomorphic adenoma: a 10-year retrospective study-a proposal for an optimal diagnostic and therapeutic algorithm for patients with recurrent pleomorphic adenoma.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2023

Research

Large carcinoma ex pleomorphic adenoma of the parotid gland: a case report and review of literature.

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2013

Research

Pleomorphic adenoma of the parotid.

American family physician, 1997

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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