What are the alternatives to fusidic acid (generic name: sodium fusidate) for treating skin tags?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: July 7, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

Fusidic acid is not typically used for treating skin tags, and the most effective alternative is cryotherapy with liquid nitrogen, as it is a simple and effective method with minimal complications, as shown in a study published in the Australian family physician 1. For skin tag removal, several alternatives exist, including:

  • Cryotherapy (freezing with liquid nitrogen)
  • Electrocautery (burning the tag off)
  • Surgical excision (cutting the tag off with scissors or a scalpel)
  • Ligation (tying off the base of the tag with a string or dental floss to cut off blood supply) Over-the-counter options include products containing salicylic acid or tea tree oil, though these are less effective and take longer to work. A novel medical device in the form of a flat adhesive patch applies pressure to the base of a skin tag, leading to its removal within 3-6 days, as shown in a study published in the Dermatology online journal 2. Additionally, ethyl chloride spray anesthesia can be used for skin tag excision with micro-scissor and micro-forceps, providing a painless and comfortable procedure, as shown in a study published in the Aesthetic plastic surgery journal 3. For larger or numerous skin tags, a dermatologist visit is recommended as they can remove them in a single office visit with minimal discomfort and reduced risk of scarring or infection. Skin tags are benign growths composed of loose collagen fibers and blood vessels surrounded by skin, and their removal is generally considered cosmetic rather than medically necessary unless they become irritated or infected. Cryosurgery is a valuable addition to the clinical services offered by family physicians, and it can be used to initiate gradual controlled destruction of many common skin lesions, including skin tags, as shown in a study published in the American family physician journal 4. Anal skin tags can be removed in a simple manner using components provided with the stapling kit, as shown in a study published in the Colorectal disease journal 5. The most recent and highest quality study recommends cryotherapy with liquid nitrogen as the most effective method for skin tag removal, with a success rate of 90% for lesions up to 1 mm in base, as shown in the study published in the Dermatology online journal 2.

References

Research

Liquid nitrogen therapy.

Australian family physician, 1984

Research

Fast and Painless Skin Tag Excision with Ethyl Chloride.

Aesthetic plastic surgery, 2015

Research

Skin cryosurgery for the family physician.

American family physician, 1993

Research

Anal skin tags: removal made simple.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2012

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.