From the FDA Drug Label
For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested: adults, 50 to 100 mg q.i.d. The recommended dose of hydroxyzine for a 19-year-old male with anxiety is 50 to 100 mg four times a day 1.
- The dose may be adjusted according to the patient's response to therapy.
- It is essential to follow the prescribed dosage and consult a healthcare professional for further guidance.
From the Research
For a 19-year-old male with anxiety, the recommended dose of hydroxyzine is 25-50 mg taken 3-4 times daily as needed, with a maximum daily dose not exceeding 400 mg, as supported by a study from 1994 2 and other evidence. The dosage range is based on the medication's efficacy in reducing anxiety symptoms, as demonstrated in various studies, including one from 1998 3 that showed hydroxyzine's superiority over placebo in generalized anxiety disorder.
- Key points to consider when prescribing hydroxyzine include:
- Starting at the lower end of the dosage range (25 mg) and adjusting based on individual response and tolerance
- Monitoring for common side effects such as drowsiness, dry mouth, and dizziness
- Avoiding combination with other central nervous system depressants like alcohol
- Regular follow-up appointments to assess effectiveness and manage side effects It's essential to note that while hydroxyzine can be effective in treating anxiety, its use should be carefully evaluated, especially in combination with other medications, as highlighted in a case report from 2024 4 that discussed the risk of priapism associated with the addition of hydroxyzine to risperidone.
- Other studies, such as those from 2007 5 and 2010 6, provide additional context on the pharmacological treatment of generalized anxiety disorders and the role of hydroxyzine, but the most relevant and recent evidence supports the recommended dosage range. Overall, hydroxyzine can be a useful treatment option for anxiety, but its use requires careful consideration of the potential benefits and risks, as well as regular monitoring and follow-up.