What are the treatment options for Lipedema (Lipodema)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 28, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

The most effective treatment for lipedema involves a comprehensive approach combining complete decongestive therapy and, in some cases, surgical intervention, prioritizing the reduction of pain, improvement of mobility, and enhancement of quality of life. When considering treatment options, it's essential to focus on managing symptoms and improving quality of life, rather than solely pursuing cosmetic outcomes. The provided evidence, although not directly focused on lipedema, highlights the importance of early detection and management of conditions like lymphedema, which shares some similarities with lipedema in terms of the need for decongestive therapy and compression therapy 1. Key components of conservative management include:

  • Manual lymphatic drainage
  • Compression therapy with garments or bandages
  • Exercise, such as regular low-impact activities like swimming, cycling, or walking
  • Skin care
  • Weight management through a healthy diet, though it's crucial to note that weight loss alone will not eliminate lipedema fat. For patients experiencing pain, over-the-counter medications like ibuprofen or acetaminophen can provide relief. In more severe cases, surgical options such as tumescent liposuction specifically designed for lipedema may be considered, aiming to remove abnormal fat tissue while preserving lymphatic vessels. Psychological support is also vital, as many patients with lipedema face body image issues and depression. Treatment plans should be highly individualized, taking into account the disease stage, symptoms, and patient preferences, with the overarching goal of improving quality of life.

From the Research

Treatment Options for Lipedema

  • Complex decongestive therapy (CDT) is considered effective in reducing intracellular and extracellular fluid volume in lipedema patients, thereby slowing down the progression of the disease 2.
  • Micro-cannular liposuction in tumescent anesthesia is a surgical option that has been shown to be effective in treating lipedema, with significant reductions in limb circumference and pain levels 3, 4.
  • Physiotherapy and rehabilitation (PR) applications, including complex decongestive physiotherapy, gait training, hydrotherapy, aerobic exercise, and resistance exercise training, have been found to be beneficial in the management of lipedema 5.
  • Lymphatic support, such as complete decongestive therapy, and specialized suction lipectomy to spare injury to lymphatic channels and remove the diseased lipedema fat are also effective treatment options for lipedema 6.

Surgical Treatment

  • Liposuction has been shown to be an effective treatment for painful lipedema, with significant improvements in pain levels, mobility, and quality of life 3, 4.
  • The procedure should be performed in specialized centers to minimize the risk of serious adverse events 3.

Non-Surgical Treatment

  • Complex decongestive therapy (CDT) is a non-surgical treatment option that aims to reduce intracellular and extracellular fluid volume in lipedema patients 2.
  • Physiotherapy and rehabilitation (PR) applications can be used in combination with other treatment modalities to manage lipedema 5.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Liposuction is an effective treatment for lipedema-results of a study with 25 patients.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2011

Research

Lipedema: A Relatively Common Disease with Extremely Common Misconceptions.

Plastic and reconstructive surgery. Global open, 2016

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.