From the Guidelines
Metrocream (metronidazole) can be used on eyelids for certain conditions, such as rosacea conjunctivitis, as part of a treatment plan that includes eyelid hygiene, warm compresses, and other therapies, as suggested by the most recent evidence 1. However, it is crucial to use it under the guidance of a healthcare provider, preferably a dermatologist or ophthalmologist, to ensure safe and effective treatment. The product labeling warns against ocular exposure, and the thin, sensitive skin of the eyelids can increase absorption of the medication, potentially leading to greater irritation or systemic effects. Some studies suggest that topical metronidazole creams and ointments may be used for rosacea conjunctivitis, in combination with other treatments such as eyelid hygiene, warm compresses, and systemic tetracyclines 1. It is essential to follow the recommended treatment plan and use the medication as directed to minimize the risk of adverse reactions. If you have a skin condition affecting your eyelids, you should consult with a healthcare provider who can recommend appropriate treatments specifically formulated for the delicate eye area. These might include specialized ophthalmic preparations that have been tested and approved for periocular use. Never apply any medication not specifically approved for use around the eyes to your eyelids without medical guidance. In the context of blepharitis treatment, the use of metronidazole is mentioned as part of the treatment options, including antiparasitic medication, in the most recent blepharitis preferred practice pattern 1. However, the primary approach to treating blepharitis involves eyelid hygiene, warm compresses, and other non-pharmacological interventions. The use of metronidazole or any other medication should be tailored to the individual patient's needs and guided by a healthcare professional.
From the FDA Drug Label
NOT FOR OPHTHALMIC USE. Avoid application close to the eyes.
The answer is no, you should not use Metrocream (metronidazole) on eyelids, as the label explicitly states it is not for ophthalmic use and to avoid application close to the eyes 2.
From the Research
Use of Metrocream on Eyelids
- Metrocream, which contains metronidazole, is typically used to treat rosacea, a condition that can affect the eyelids [(3,4,5,6,7)].
- There is evidence to suggest that metronidazole can be used to treat blepharitis, an inflammation of the eyelids, particularly when caused by Demodex folliculorum 3.
- A study published in 1998 found that a combination of lid scrubs and 2% metronidazole gel was effective in relieving symptoms of chronic Demodex blepharoconjunctivitis 3.
- However, it is essential to note that the use of Metrocream on the eyelids may not be explicitly approved, and caution should be exercised to avoid any potential irritation or side effects 7.
- As with any medication, it is crucial to follow the recommended usage and consult a healthcare professional before using Metrocream on the eyelids [(4,5,6)].
Key Considerations
- Metronidazole has been shown to be effective in treating rosacea and blepharitis [(3,4,5,6,7)].
- The medication is generally well-tolerated, but local reactions such as burning and stinging can occur 7.
- It is essential to consult a healthcare professional before using Metrocream on the eyelids to ensure safe and effective treatment [(4,5,6)].