Is a low total lymphocyte count (TLC) associated with adult maltreatment?

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Last updated: February 8, 2025View editorial policy

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From the Research

Association between Low Total Lymphocyte Count and Adult Maltreatment

There is limited direct evidence to suggest a link between low total lymphocyte count (TLC) and adult maltreatment. However, several studies have investigated the relationship between TLC and various health outcomes, including malnutrition, cancer, and infectious diseases.

Relevant Studies

  • A study published in 2021 1 found that malnutrition was associated with lower TLC in patients with COVID-19, suggesting that nutritional status may play a role in TLC.
  • Another study from 2017 2 found that TLC was correlated with nutritional markers, including mid-upper arm circumference and triceps skinfold thickness, in hospitalized older adults.
  • A study from 2013 3 found that low TLC was associated with poor survival in patients with resected pancreatic adenocarcinoma receiving immunotherapy.
  • A study from 2008 4 found that low TLC was associated with in-hospital mortality in older persons with multimorbidity, independently of the presence of multiple co-existing diseases.
  • A study from 2005 5 suggested that TLC could be used as an independent criterion for initiating antiretroviral treatment in resource-poor countries.

Key Findings

  • Low TLC has been associated with poor health outcomes, including malnutrition, cancer, and infectious diseases.
  • Nutritional status may play a role in TLC, with malnutrition contributing to lower TLC.
  • TLC has been correlated with nutritional markers, including mid-upper arm circumference and triceps skinfold thickness.
  • Low TLC has been associated with increased risk of in-hospital mortality in older persons with multimorbidity.

Implications

  • Further research is needed to investigate the relationship between TLC and adult maltreatment.
  • TLC may be a useful marker for monitoring health outcomes in various populations, including older adults and those with malnutrition or infectious diseases.
  • Nutritional interventions may be important for maintaining healthy TLC levels and preventing poor health outcomes.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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