From the FDA Drug Label
Pharmacokinetic parameters of oxybutynin and desethyloxybutynin (Cmax and AUC) following administration of 5 to 20 mg of oxybutynin chloride extended release tablets are dose proportional The answer is yes, oxybutynin comes in a 20mg dosage, as indicated by the dose proportionality of oxybutynin chloride extended release tablets ranging from 5 to 20 mg 1.
From the Research
No, oxybutynin is not available in a 20mg single dosage form. Oxybutynin, an antimuscarinic medication commonly used to treat overactive bladder and urinary incontinence, is typically available in immediate-release tablets of 5mg, extended-release tablets of 5mg, 10mg, and 15mg, and as a transdermal patch delivering 3.9mg per day. The maximum recommended daily dose for immediate-release oxybutynin is usually 5mg taken 2-3 times daily (10-15mg total per day), while extended-release formulations are generally prescribed up to 30mg daily in some cases, but administered as multiple tablets rather than a single 20mg dose, as noted in a study published in the journal Drugs 2. Patients requiring higher doses would need to take multiple tablets to achieve the desired therapeutic effect. The dosing limitations reflect the balance between efficacy and managing side effects like dry mouth, constipation, and blurred vision, which are common with antimuscarinic medications and tend to increase at higher doses. Some key points to consider when prescribing oxybutynin include:
- The efficacy of oxybutynin in treating overactive bladder symptoms, as demonstrated in studies such as the one published in the journal BJU international 3
- The importance of considering the patient's individual needs and medical history when selecting a dosage and formulation of oxybutynin, as discussed in the journal Therapeutics and clinical risk management 4
- The potential for side effects and the need for careful monitoring and dose adjustment, as noted in the study published in The Journal of urology 5