Can I use calcium alginate, honey, (Absorbent Dressing) ABD, and Kerlix to dress a stage three wound on the plantar foot?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: July 8, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Management of Stage Three Wound on Plantar Foot

Do not use calcium alginate, honey, ABD, and Kerlix combination for a stage three wound on the plantar foot as there is insufficient evidence to support this dressing combination for wound healing. 1

Evidence-Based Dressing Selection

The 2023 International Working Group on the Diabetic Foot (IWGDF) guidelines provide clear recommendations against using specific dressing components you've mentioned:

  1. Alginate dressings: "Do not use collagen or alginate dressings for the purpose of wound healing of diabetes-related foot ulcers" (Strong recommendation; Low certainty evidence) 1

  2. Honey products: "Do not use honey (or bee-related products) for the purpose of wound healing in diabetes-related foot ulcers" (Strong recommendation; Low certainty evidence) 1

  3. Basic absorbent dressings: While ABD (absorbent dressing) and Kerlix (gauze) are basic dressings that can be used for exudate management, they should be selected based on specific wound characteristics rather than as a standard combination.

Rationale Behind Recommendations

Alginate Dressings

Multiple studies examining alginate dressings found no convincing evidence of benefit for diabetic foot ulcers. A Cochrane review concluded that "there is no research evidence to suggest that alginate wound dressings are more effective in healing foot ulcers in people with diabetes than other types of dressing" 2. The IWGDF reviewed 12 RCTs of collagen or alginate dressings and found that 9 of them showed no difference in wound healing outcomes 1.

Honey Products

Despite honey's theoretical anti-inflammatory and antimicrobial properties, the evidence doesn't support its use for wound healing. The IWGDF found that all studies on honey products were at high risk of bias, and the only blinded study showed no difference in healing 1. A Cochrane review suggested "health services may wish to consider avoiding routine use of honey dressings until sufficient evidence of effect is available" 1.

Basic Dressings (ABD and Kerlix)

While basic dressings have a role in wound care, they should be selected based on exudate control, comfort, and cost rather than as a standard approach 1.

Recommended Approach for Stage Three Plantar Foot Wounds

  1. Primary intervention: Sharp debridement of slough, necrotic tissue, and surrounding callus (Strong recommendation) 1

  2. Dressing selection: Choose dressings based on:

    • Exudate control needs
    • Patient comfort
    • Cost-effectiveness 1
  3. For difficult-to-heal wounds: Consider sucrose-octasulfate impregnated dressing as an adjunctive treatment for non-infected, neuro-ischemic diabetic foot ulcers that haven't responded to standard care for at least 2 weeks 1

Common Pitfalls to Avoid

  1. Using unproven combinations: Combining multiple dressing types (like alginate + honey) without evidence may increase costs without improving outcomes.

  2. Neglecting offloading: The most important intervention for plantar wounds is proper offloading, which is often overlooked in favor of focusing on dressing selection.

  3. Overlooking infection: Stage three wounds have higher infection risk. Ensure proper assessment for infection before focusing on dressing selection.

  4. Delayed debridement: Sharp debridement should be prioritized over advanced dressings for removing necrotic tissue and promoting healing.

In conclusion, while the proposed combination of calcium alginate, honey, ABD, and Kerlix might seem comprehensive, current evidence does not support this approach for enhancing wound healing in stage three plantar foot wounds. Instead, focus on proper debridement, appropriate offloading, and selecting dressings based on wound characteristics and exudate management needs.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Alginate dressings for healing diabetic foot ulcers.

The Cochrane database of systematic reviews, 2012

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.