Management of Tick Bites
Prophylactic antibiotic therapy should only be given for high-risk tick bites within 72 hours of tick removal, not for all tick bites. 1
Assessment of Tick Bite Risk
To determine if antibiotic prophylaxis is needed, assess if the tick bite meets ALL three criteria for high-risk:
- Tick species: Must be identified as Ixodes species (deer tick/black-legged tick)
- Geographic location: Must have occurred in a highly endemic area for Lyme disease
- Duration of attachment: Must have been attached for ≥36 hours 1
If ALL three criteria are met, prophylactic treatment is recommended. If ANY criterion is not met or cannot be determined with certainty, a wait-and-watch approach is recommended.
Immediate Management
Remove the tick promptly:
- Use clean fine-tipped tweezers or a commercial tick removal device
- Grasp the tick as close to the skin as possible
- Pull upward with steady, even pressure
- Do NOT burn the tick or apply chemicals 1
Preserve the tick for identification:
- Submit the removed tick for species identification 1
- This helps determine risk level and need for prophylaxis
Prophylactic Treatment
For high-risk tick bites meeting ALL criteria above:
- Medication: Single dose of oral doxycycline
- Timing: Must be given within 72 hours of tick removal
- Dosage:
- Adults: 200 mg as a single dose
- Children: 4.4 mg/kg (maximum 200 mg) as a single dose 1
Post-Bite Monitoring
If prophylaxis is not indicated or not given:
- Monitor for symptoms for at least 30 days
- Watch for:
- Erythema migrans (bull's-eye rash)
- Fever, headache, fatigue, muscle/joint pain
- Any other unusual symptoms 1
Special Considerations
- Testing after tick bite: Testing asymptomatic patients for B. burgdorferi following a tick bite is NOT recommended 1
- Southern Tick-Associated Rash Illness (STARI): In areas where both STARI and Lyme disease are endemic, if the responsible tick cannot be identified, treat as Lyme disease 1
- Rocky Mountain Spotted Fever areas: Prophylactic antibiotics are not recommended, but seek medical attention at first sign of fever or rash 1
Prevention of Future Tick Bites
- Use EPA-registered repellents (DEET, picaridin, IR3535, oil of lemon eucalyptus, PMD, 2-undecanone)
- Apply permethrin to clothing and gear
- Wear long sleeves and pants in tick-prone areas
- Perform thorough tick checks after outdoor activities 1
Common Pitfalls to Avoid
- Overuse of antibiotics: Not all tick bites require prophylaxis - only those meeting all high-risk criteria
- Delayed tick removal: Remove ticks as soon as possible, as risk increases with attachment time
- Improper removal techniques: Never burn ticks or apply petroleum jelly
- Missing the prophylaxis window: Antibiotic prophylaxis is ineffective if given more than 72 hours after tick removal
- Unnecessary testing: Testing asymptomatic individuals after tick bites is not recommended and may lead to false positives or negatives 1
Remember that even with prophylaxis, monitoring for symptoms remains important as prophylaxis is not 100% effective in preventing Lyme disease.