What is the likely cause of a 27-year-old woman's left-sided pelvic pain, amenorrhea (absence of menstruation), nausea, and tender left adnexal mass?

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Differential Diagnosis for Pelvic Pain in a 27-year-old Woman

  • Single most likely diagnosis
    • Ectopic pregnancy: The combination of pelvic pain, amenorrhea, and a tender adnexal mass is highly suggestive of an ectopic pregnancy, which occurs when a fertilized egg implants outside the uterus, often in the fallopian tube.
  • Other Likely diagnoses
    • Ovarian cyst or torsion: A tender adnexal mass could also represent an ovarian cyst that has ruptured or become twisted, cutting off its blood supply.
    • Pelvic inflammatory disease (PID): PID, often caused by sexually transmitted infections, can lead to pelvic pain, adnexal tenderness, and sometimes a palpable mass if an abscess has formed.
    • Endometriosis: While less likely to cause a distinct adnexal mass, endometriosis can lead to pelvic pain, especially if there are endometriomas (cysts filled with old blood) on the ovaries.
  • Do Not Miss
    • Ruptured ectopic pregnancy: This is a medical emergency that requires immediate surgical intervention. The symptoms can initially be similar to those of a non-ruptured ectopic pregnancy but can quickly escalate to severe abdominal pain, shock, and even death if not promptly treated.
    • Ovarian torsion: This condition, where the ovary twists around its ligaments, cutting off blood supply, is an emergency that requires immediate surgical intervention to save the ovary and prevent further complications.
    • Appendicitis: Although the pain is typically more right-sided, appendicitis can sometimes present with pelvic pain and must be considered, especially if the pain is severe and accompanied by fever and vomiting.
  • Rare diagnoses
    • Malignant ovarian tumor: While rare in young women, ovarian cancer can present with pelvic pain and a palpable mass.
    • Tubo-ovarian abscess: A complication of PID where the infection collects in the fallopian tube and ovary, forming an abscess, which is a rare but serious condition requiring prompt antibiotic treatment and possibly drainage.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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