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Differential Diagnosis for Autoimmune Disorder with Frequent Passing Out

  • Single most likely diagnosis
    • Postural Orthostatic Tachycardia Syndrome (POTS): This condition is often associated with autoimmune disorders and can cause frequent passing out due to a sudden drop in blood pressure when standing up. It's a common cause of orthostatic intolerance in patients with autoimmune diseases.
  • Other Likely diagnoses
    • Autoimmune Autonomic Ganglionopathy: This is a rare autoimmune disorder that affects the autonomic nervous system, leading to orthostatic intolerance and potentially causing frequent passing out.
    • Multiple System Atrophy (MSA): Although not exclusively an autoimmune disorder, MSA can have autoimmune components and causes autonomic dysfunction, including orthostatic hypotension, which may lead to passing out.
  • Do Not Miss diagnoses
    • Addison's Disease: An autoimmune disorder that causes adrenal insufficiency, potentially leading to hypotension and passing out. Missing this diagnosis could be life-threatening due to the risk of adrenal crisis.
    • Myasthenia Gravis: An autoimmune neuromuscular disorder that can cause muscle weakness, potentially affecting respiratory and bulbar muscles, leading to sudden loss of consciousness.
  • Rare diagnoses
    • Autoimmune Hypopituitarism: A rare condition where the immune system attacks the pituitary gland, potentially leading to various hormonal deficiencies, including adrenal insufficiency, which could cause passing out.
    • Stiff Person Syndrome: A rare autoimmune disorder characterized by progressive stiffness and rigidity of the muscles, which can lead to impaired mobility and potentially cause falls or passing out due to loss of balance.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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