Recommended Dosage of Robaxin (Methocarbamol) for Adults
For adults, the recommended dose of Robaxin (methocarbamol) is initially 1500 mg (three 500 mg tablets) four times daily, followed by a maintenance dose of 1000 mg (two 500 mg tablets) four times daily. 1
Dosing Guidelines
The FDA-approved dosing for methocarbamol follows two main formulations:
For 500 mg tablets:
- Initial dosage: 3 tablets (1500 mg) 4 times daily
- Maintenance dosage: 2 tablets (1000 mg) 4 times daily
For 750 mg tablets:
- Initial dosage: 2 tablets (1500 mg) 4 times daily
- Maintenance dosage: 1 tablet every 4 hours or 2 tablets 3 times daily
Treatment Duration and Maximum Dosage
- First 48-72 hours: Six grams daily is recommended
- For severe conditions: Up to 8 grams daily may be administered initially
- After initial period: Dosage can usually be reduced to approximately 4 grams daily
Special Considerations
Safety Concerns
- Methocarbamol can cause sedative effects and may interact with other central nervous system depressants
- Particular caution should be exercised when combining with alcohol, as this combination can lead to enhanced central nervous system depression 2
Monitoring
- Patients should be monitored for signs of excessive sedation, especially during the initial treatment period
- Dose adjustments may be necessary based on individual response and tolerability
Contraindications
- Known hypersensitivity to methocarbamol or related compounds
- Caution in patients with impaired renal or hepatic function
Practical Administration Tips
- Methocarbamol can be taken with or without food
- If gastrointestinal upset occurs, taking with food may help reduce these effects
- The medication should be taken at evenly spaced intervals throughout the day to maintain therapeutic blood levels
This dosing information is based on the FDA-approved drug label, which provides the most current and authoritative guidance for methocarbamol administration in adults.