Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: July 9, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Vaginal Bleeding

Single Most Likely Diagnosis

  • Menstrual irregularity: This is the most common cause of vaginal bleeding, especially in women of reproductive age, due to hormonal changes or irregular ovulation.

Other Likely Diagnoses

  • Pregnancy-related complications (e.g., miscarriage, ectopic pregnancy): These conditions can cause vaginal bleeding due to implantation issues or complications with the pregnancy.
  • Infections (e.g., pelvic inflammatory disease, cervicitis): Infections can lead to inflammation and bleeding in the reproductive tract.
  • Hormonal imbalances (e.g., polycystic ovary syndrome, thyroid disorders): Hormonal changes can disrupt the normal menstrual cycle, leading to irregular bleeding.
  • Contraceptive-related bleeding: Certain contraceptives, such as intrauterine devices (IUDs) or hormonal birth control, can cause irregular bleeding.

Do Not Miss Diagnoses

  • Ectopic pregnancy: Although not the most common cause, ectopic pregnancy is a life-threatening condition that requires immediate attention.
  • Malignancy (e.g., cervical, uterine, or ovarian cancer): Cancer can cause abnormal vaginal bleeding, and early detection is crucial for effective treatment.
  • Placenta previa or placental abruption: These pregnancy complications can cause severe bleeding and require prompt medical attention.
  • Uterine rupture or perforation: Although rare, these conditions can be life-threatening and require immediate surgical intervention.

Rare Diagnoses

  • Uterine arteriovenous malformation: A rare vascular anomaly that can cause abnormal bleeding.
  • Von Willebrand disease or other bleeding disorders: These conditions can increase the risk of heavy or prolonged menstrual bleeding.
  • Foreign body or trauma: Rarely, a foreign object or trauma to the reproductive tract can cause vaginal bleeding.
  • Endometrial hyperplasia or polyps: Although not typically life-threatening, these conditions can cause abnormal bleeding and may increase the risk of malignancy.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.