What is the cause of severe abdominal pain and hematemesis in a 45-year-old male with multiple laparotomy scars and normal hemoglobin levels?

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Differential Diagnosis

  • Single most likely diagnosis
    • Peptic ulcer disease: The patient's symptoms of severe abdominal pain and vomiting large amounts of fresh blood are classic for a bleeding peptic ulcer. The presence of several laparotomy scars suggests a history of abdominal surgeries, which could be related to previous peptic ulcer disease or its complications.
  • Other Likely diagnoses
    • Gastroesophageal varices: Although the patient is well perfused and has a normal hemoglobin level, the history of vomiting large amounts of blood could still suggest bleeding from gastroesophageal varices, especially if the patient has a history of liver disease.
    • Mallory-Weiss syndrome: This condition, characterized by tears in the mucous membrane of the lower end of the esophagus, could cause vomiting blood, especially if the patient has a history of intense or prolonged vomiting.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Aortic dissection or rupture: Although the patient's symptoms do not directly suggest this diagnosis, severe abdominal pain can be a presentation of aortic dissection or rupture, which would be catastrophic if missed.
    • Mesenteric ischemia: This condition, which involves insufficient blood flow to the intestines, can cause severe abdominal pain and vomiting, and would require prompt diagnosis and treatment to prevent serious complications.
    • Boerhaave's syndrome: This condition, characterized by a spontaneous rupture of the esophagus, can cause severe chest or abdominal pain and vomiting blood, and would require immediate surgical intervention.
  • Rare diagnoses
    • Dieulafoy's lesion: This rare condition, characterized by a small, bleeding ulcer in the stomach or intestine, could cause vomiting blood, but is less likely than other diagnoses.
    • Hemobilia: This condition, characterized by bleeding into the biliary tree, could cause vomiting blood, but is relatively rare and would typically be associated with other symptoms such as jaundice.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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