What causes xerostomia (dry mouth) in the morning?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 28, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Dry Mouth in the Morning

  • Single Most Likely Diagnosis
    • Dehydration: This is often the most common cause of dry mouth, especially in the morning. It can be due to not drinking enough water during the day or night, leading to a decrease in saliva production.
  • Other Likely Diagnoses
    • Sleep with mouth open: Sleeping with the mouth open can cause dry mouth due to evaporation of saliva.
    • Medication side effects: Many medications, such as antihistamines, decongestants, and antidepressants, can cause dry mouth as a side effect.
    • Mouth breathing: Breathing through the mouth instead of the nose can dry out the mouth and throat.
    • Aging: Older adults may experience a decrease in saliva production, leading to dry mouth.
  • Do Not Miss Diagnoses
    • Sjögren's syndrome: An autoimmune disorder that can cause dry mouth and eyes.
    • Diabetes: Uncontrolled diabetes can cause dry mouth due to high blood sugar levels.
    • Hypothyroidism: An underactive thyroid gland can cause dry mouth, among other symptoms.
    • Sleep apnea: This condition can cause mouth breathing and dry mouth.
  • Rare Diagnoses
    • Sarcoidosis: A rare autoimmune disorder that can cause dry mouth, among other symptoms.
    • Amyloidosis: A rare condition that can cause dry mouth, among other symptoms.
    • Radiation therapy: Radiation to the head and neck can cause dry mouth due to damage to the salivary glands.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.