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Differential Diagnosis for Bullous Lesions on Fingers

  • Single Most Likely Diagnosis
    • Dyshidrotic Eczema (Pompholyx): This condition is characterized by the appearance of small, itchy blisters (vesicles) on the palms of the hands and soles of the feet, which can also extend to the fingers. It's a common condition that can be triggered by stress, allergies, or exposure to certain metals.
  • Other Likely Diagnoses
    • Contact Dermatitis: An allergic reaction or irritation from substances like detergents, soaps, or certain metals can cause bullous lesions on the fingers.
    • Bullous Impetigo: A bacterial infection of the skin that can cause blisters, especially in children.
    • Herpes Simplex: Although more commonly associated with oral or genital areas, herpes simplex can occasionally cause lesions on the fingers, known as herpetic whitlow.
  • Do Not Miss Diagnoses
    • Erythema Multiforme: A skin condition that can be triggered by infections or medications, characterized by target-like lesions, which can sometimes appear bullous.
    • Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN): Severe skin conditions usually triggered by medications, leading to widespread skin necrosis and detachment, which can start with bullous lesions.
    • Autoimmune Bullous Diseases (e.g., Pemphigus, Bullous Pemphigoid): These are rare but serious conditions that can cause blistering of the skin and mucous membranes.
  • Rare Diagnoses
    • Epidermolysis Bullosa: A group of genetic conditions that result in fragile skin and blisters.
    • Bullous Drug Eruptions: Certain medications can cause bullous skin reactions as a side effect.
    • Acute Porphyrias: A group of rare genetic disorders that can cause blistering of the skin upon exposure to sunlight, among other symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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