What are the components of Infuvite (multivitamin infusion)?

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Components of Infuvite (Multivitamin Infusion)

Infuvite is a parenteral multivitamin formulation containing both water-soluble and fat-soluble vitamins designed to prevent vitamin deficiencies in patients requiring intravenous nutrition.

Water-Soluble Vitamins in Infuvite

Infuvite contains the following water-soluble vitamins 1:

  • Vitamin B1 (Thiamine): 2.5-6 mg
  • Vitamin B2 (Riboflavin): 3.6 mg
  • Vitamin B3 (Niacin): 40 mg
  • Vitamin B5 (Pantothenic acid): 15 mg
  • Vitamin B6 (Pyridoxine): 4-6 mg
  • Vitamin B7 (Biotin): 60 μg
  • Vitamin B9 (Folic acid): 400-600 μg
  • Vitamin B12 (Cyanocobalamin): 5-7.5 μg
  • Vitamin C (Ascorbic acid): 100-200 mg

Fat-Soluble Vitamins in Infuvite

Infuvite also contains the following fat-soluble vitamins 1:

  • Vitamin A: Typically provided as retinol
  • Vitamin D: In standardized amounts
  • Vitamin E: Provided as alpha-tocopherol
  • Vitamin K: 10 μg/kg for infants and children, 200 μg for adults

Clinical Considerations

When administering Infuvite:

  • Water-soluble vitamins must be administered regularly as they are not stored in significant amounts (except B12) 1
  • The administration of multivitamins with intravenous lipid emulsions provides a practical way to reduce peroxidation of the lipid while limiting vitamin loss 1
  • Vitamin C demonstrates instability after 48 hours when stored at 25°C 1

Special Population Considerations

Pediatric Dosing

For pediatric patients, Infuvite dosing is weight-based 1:

  • Preterm and term infants up to 12 months: Adjusted doses per kg
  • Children and adolescents: Standardized doses

Critical Illness

During critical illness and in patients with acute malnutrition, increased requirements for certain vitamins may be necessary for up to 15 days as repletion therapy 1.

Important Caveats

  • Thiamine should always be administered before glucose in patients at risk for deficiency to prevent precipitating Wernicke's encephalopathy 1
  • Vitamin stability can be affected by storage conditions, with vitamin C being particularly susceptible to degradation 1
  • Parenteral doses of water-soluble vitamins are generally several times higher than oral recommended daily allowances due to higher requirements and increased urinary excretion 1

The intravenous route allows for direct delivery of vitamins into the bloodstream, bypassing potential absorption issues that might occur with oral administration, which is particularly important in patients with malabsorption syndromes or critical illness 2.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Intravenous vitamin injections: where is the evidence?

Drug and therapeutics bulletin, 2023

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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