What are bioregulators?

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Last updated: February 28, 2025View editorial policy

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From the FDA Drug Label

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From the Research

Bioregulators are naturally occurring organic compounds that regulate diverse cellular processes, including peptides, cytokines, eicosanoids, neurotransmitters, hormones, and proteolytic enzymes, which can have profound physiologic effects if exploited for bioterrorism purposes. These compounds are essential for physiologic homeostasis and can be found in various living organisms, including plants and animals 1. The main groups of bioregulators include:

  • Cytokines
  • Eicosanoids
  • Neurotransmitters
  • Hormones
  • Proteolytic enzymes They work by binding to specific receptors on cell surfaces or within cells to influence gene expression, protein synthesis, and cellular metabolism 2, 3, 4. Some bioregulators, such as plant growth bioregulators, can affect both plant and animal reign, and their structure-activity and effects on mammals have been studied 1. However, the potential misuse of bioregulators for nefarious purposes, such as bioterrorism, is a concern due to their ability to induce profound physiologic effects within minutes of administration 2, 3, 4. It is essential to note that while bioregulators have potential applications in medicine, their regulatory status varies widely, and research on their efficacy and safety is still developing in many cases. The most recent study on bioregulators, published in 2024, highlights the importance of understanding the structure-activity and effects of these compounds on mammals 1. In contrast, other studies have focused on the potential risks associated with bioregulators, such as their potential use as nontraditional threat agents 2, 3, 4. Overall, bioregulators are complex compounds that play a crucial role in regulating various biological functions, and their potential applications and risks need to be carefully considered. The concept behind bioregulators is that they can help maintain homeostasis by supporting the body's natural regulatory mechanisms, which is essential for preventing diseases and promoting overall health 1. In the context of real-life clinical medicine, it is crucial to prioritize the potential benefits and risks of bioregulators and to consider the most recent and highest-quality evidence when making decisions about their use 1.

References

Research

Bioregulators as instruments of terror.

Clinics in laboratory medicine, 2001

Research

The toxicology of bioregulators as potential agents of bioterrorism.

Arhiv za higijenu rada i toksikologiju, 2005

Research

Bioregulators as prototypic nontraditional threat agents.

Clinics in laboratory medicine, 2006

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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