Differential Diagnosis for Bibasilar Pulmonary Infiltrates
Single Most Likely Diagnosis
- Heart Failure: This is often the most common cause of bibasilar pulmonary infiltrates, particularly in patients with a history of cardiovascular disease. The infiltrates are typically due to pulmonary edema resulting from left ventricular dysfunction.
Other Likely Diagnoses
- Pneumonia: Both community-acquired and hospital-acquired pneumonias can present with bibasilar infiltrates, especially if the causative organisms are Streptococcus pneumoniae, Haemophilus influenzae, or Moraxella catarrhalis.
- Chronic Obstructive Pulmonary Disease (COPD) Exacerbation: Patients with COPD can develop bibasilar infiltrates during exacerbations, often due to increased secretions and inflammation.
- Interstitial Lung Disease (ILD): Certain types of ILD, such as idiopathic pulmonary fibrosis, can present with bibasilar infiltrates on chest imaging.
Do Not Miss Diagnoses
- Pulmonary Embolism: Although pulmonary embolism typically presents with unilateral infiltrates or no infiltrates at all, it can occasionally cause bibasilar infiltrates, especially if there are multiple small emboli. Missing this diagnosis can be fatal.
- Acute Respiratory Distress Syndrome (ARDS): This is a life-threatening condition that can cause bilateral infiltrates, including bibasilar patterns. It requires immediate recognition and treatment.
- Inhalation Injury: In patients with a history of smoke inhalation or exposure to toxic gases, bibasilar infiltrates can be a sign of inhalation injury, which is a medical emergency.
Rare Diagnoses
- Lymphangitic Carcinomatosis: This rare condition involves the spread of cancer to the lymphatic vessels of the lungs, which can cause bibasilar infiltrates.
- Eosinophilic Pneumonia: A rare condition characterized by the accumulation of eosinophils in the lungs, which can present with bibasilar infiltrates.
- Alveolar Proteinosis: A rare disease characterized by the accumulation of surfactant-like protein and phospholipids in the alveoli, which can cause bibasilar infiltrates on chest imaging.