What is Phenylpiracetam (Nootropic agent)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 28, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

Phenylpiracetam is a synthetic nootropic drug that is a modified version of piracetam with an added phenyl group, making it more potent and providing mild stimulant effects, and its use should be approached with caution due to potential side effects and interactions, as noted in recent studies 1.

Overview of Phenylpiracetam

Phenylpiracetam is used in some countries like Russia as a prescription medication (under names like Fonturacetam or Carphedon) for cognitive enhancement, treating cognitive decline, and improving physical performance.

Dosage and Effects

Typical dosages range from 100-200mg taken 1-2 times daily, with a maximum daily dose of 600mg recommended by those who use it. The effects typically last 4-6 hours.

Mechanism of Action

Phenylpiracetam works by modulating neurotransmitters like acetylcholine, dopamine, and GABA, while also potentially increasing brain-derived neurotrophic factor, as discussed in a study on its pharmacological effects 1.

Precautions and Side Effects

Users should be aware that tolerance develops quickly with daily use, so cycling the compound (using it for 1-2 weeks followed by a break) is often recommended. Side effects may include headaches, irritability, insomnia, and gastrointestinal discomfort. Due to its stimulant properties, it's banned by the World Anti-Doping Agency for competitive athletes. Those interested should consult a healthcare provider before use, especially if taking other medications or having underlying health conditions, considering the potential benefits and risks outlined in recent research 1.

Clinical Use and Prospects

The adaptogenic properties and mitochondrial protective effect of Phenylpiracetam are considered, assessments of the possible effect of Phenylpiracetam on neurotransmitter systems, regulation of carbohydrate and fat metabolism with the prospects for the use of Phenylpiracetam in patients with metabolic syndrome, as noted in a recent analysis of experimental and clinical studies 1.

References

Research

[Pharmacological effects of fonturacetam (Actitropil) and prospects for its clinical use].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2024

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.