From the Research
Serum Creatinine Levels in Individuals with a Solitary Kidney
- The average serum creatinine level in a person with a solitary kidney is not explicitly stated in the provided studies, but various studies report different levels:
- A study from 2008 1 found that serum creatinine levels increased significantly with increasing age in patients with a single functioning kidney.
- A study from 2007 2 reported a median preoperative creatinine level of 1.4 mg/dL in patients with a solitary kidney undergoing radiofrequency ablation.
- Another study from 2007 3 found that the mean serum creatinine level increased from 1.25 mg/dl preoperatively to 1.62 mg/dl postoperatively in patients with renal cell carcinoma in a solitary kidney who underwent nephron-sparing surgery.
- These studies suggest that serum creatinine levels can vary depending on the individual and the underlying condition of the solitary kidney.
Factors Affecting Serum Creatinine Levels
- Several factors can affect serum creatinine levels in individuals with a solitary kidney, including:
- Age: Serum creatinine levels tend to increase with age 1.
- Underlying kidney disease: Patients with obstructive uropathy tend to have higher serum creatinine levels 1.
- Treatment: Certain treatments, such as radiofrequency ablation 2 or nephron-sparing surgery 3, can affect serum creatinine levels.
- Tumor size: Larger tumors are associated with higher serum creatinine levels and a greater risk of disease progression 3.
Renal Function in Individuals with a Solitary Kidney
- Renal function can be affected in individuals with a solitary kidney, with some studies reporting a decline in renal function over time:
- A study from 1994 4 found that patients with a solitary kidney who underwent extracorporeal shock wave lithotripsy experienced a significant decline in renal function over time.
- A study from 2019 5 found that individuals with a solitary kidney were at increased risk of developing chronic kidney disease.