What are the causes of wheezing and squeaking sounds when inhaling, also known as stridor (high-pitched sound) and wheezing (high-pitched whistling sound)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: February 28, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Wheezing and Squeaking when Breathing In

  • Single Most Likely Diagnosis
    • Asthma: This is the most common cause of wheezing and is often associated with squeaking sounds when breathing in, especially during an asthma attack. The wheezing is typically bilateral and can be accompanied by coughing, shortness of breath, and chest tightness.
  • Other Likely Diagnoses
    • Chronic Obstructive Pulmonary Disease (COPD): COPD can cause wheezing, particularly in advanced stages, due to the obstruction of airflow. Squeaking sounds may be less common but can occur, especially during exacerbations.
    • Bronchiolitis: This condition, often seen in children, involves inflammation of the small airways and can cause wheezing and squeaking sounds due to the narrowing of these airways.
    • Allergic Rhinitis: Although primarily causing nasal symptoms, severe allergic reactions can lead to lower respiratory tract involvement, resulting in wheezing and possibly squeaking sounds when breathing in.
  • Do Not Miss Diagnoses
    • Foreign Body Aspiration: This is a medical emergency, especially in children, where an inhaled object can cause sudden onset of wheezing and squeaking sounds due to airway obstruction. Prompt diagnosis and removal of the foreign body are crucial.
    • Pneumonia: Certain types of pneumonia, especially those caused by viral or mycoplasma infections, can present with wheezing. Squeaking sounds might be less typical but can occur, particularly if there's significant airway involvement.
    • Pulmonary Embolism: Although wheezing is not a classic symptom, in rare cases, pulmonary embolism can cause wheezing due to the sudden blockage of an artery in the lungs, leading to infarction and possible airway irritation.
  • Rare Diagnoses
    • Vocal Cord Dysfunction: This condition can mimic asthma and cause wheezing or stridor (a high-pitched sound) when breathing in, due to abnormal movement of the vocal cords.
    • Tracheomalacia: A condition where the trachea is soft and collapsible, potentially causing wheezing and squeaking sounds, especially during breathing.
    • Bronchiectasis: A condition characterized by damaged, dilated airways, which can lead to chronic infections and, in some cases, wheezing and abnormal breath sounds.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.