Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: July 10, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Lower Abdominal Pain and Diarrhea

Single Most Likely Diagnosis

  • Viral Gastroenteritis: This is the most likely diagnosis given the symptoms of lower abdominal pain, diarrhea, and a low-grade fever. The short duration of symptoms (2 days) and the presence of a fever also support this diagnosis, as viral gastroenteritis is a common and often self-limiting condition.

Other Likely Diagnoses

  • Bacterial Gastroenteritis: Similar to viral gastroenteritis but caused by bacteria. The symptoms can be more severe, and the presence of blood in the stool or a higher fever might suggest a bacterial cause.
  • Inflammatory Bowel Disease (IBD) Flare: Conditions like Crohn's disease or ulcerative colitis can present with abdominal pain and diarrhea. However, these conditions typically have a longer history, and the onset might not be as acute.
  • Irritable Bowel Syndrome (IBS): Although IBS can cause chronic abdominal pain and changes in bowel habits, the acute onset of symptoms and the presence of a fever are less typical for IBS.

Do Not Miss Diagnoses

  • Appendicitis: Although the pain is described as lower abdominal, appendicitis can sometimes present with pain that is more diffuse or in the lower abdomen, especially if the appendix is in a retrocecal position. The presence of fever and abdominal pain necessitates considering appendicitis to avoid missing this potentially life-threatening condition.
  • Diverticulitis: Inflammation of a diverticulum in the colon can cause lower abdominal pain, fever, and changes in bowel habits. This condition is more common in older adults and requires prompt medical attention.
  • Intestinal Obstruction: This is a condition where the intestine is partially or completely blocked, which can cause severe abdominal pain, vomiting, and changes in bowel habits. The presence of fever might indicate an obstructive process complicated by infection.

Rare Diagnoses

  • Yersiniosis: A bacterial infection caused by Yersinia enterocolitica, which can mimic appendicitis with lower right quadrant abdominal pain and fever.
  • Intussusception: A condition where a part of the intestine slides into an adjacent part, potentially causing bowel obstruction. It's rare in adults but can occur, especially in the context of a lead point like a tumor.
  • Mesenteric Lymphadenitis: Inflammation of the lymph nodes in the mesentery can cause abdominal pain and fever, often mimicking appendicitis. It's more common in children but can occur in adults.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.