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Last updated: July 10, 2025View editorial policy

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Differential Diagnosis for Sore Under Breast

  • Single most likely diagnosis
    • Intertrigo: This is the most common cause of soreness under the breast, especially in warm and humid environments. It is a type of skin inflammation caused by friction, moisture, and bacterial or fungal infections.
  • Other Likely diagnoses
    • Eczema (atopic dermatitis): Can cause itchy, inflamed skin under the breast.
    • Contact dermatitis: Irritation from bras, soaps, or other substances can lead to a sore under the breast.
    • Folliculitis: Inflammation of the hair follicles, often due to bacterial infection, can cause soreness and redness.
    • Breast abscess or infected cyst: Though less common, an abscess or infected cyst under the breast can cause significant pain and soreness.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Inflammatory breast cancer: A rare but aggressive form of breast cancer that can cause skin changes, including redness and soreness under the breast.
    • Lymphoma: Though rare, lymphoma can manifest with skin symptoms, including soreness under the breast.
    • Tuberculosis or other systemic infections: In rare cases, systemic infections can cause skin lesions or soreness under the breast.
  • Rare diagnoses
    • Hidradenitis suppurativa: A chronic skin condition that can cause painful abscesses and nodules in areas of the body with apocrine glands, including under the breast.
    • Actinomycosis: A rare bacterial infection that can cause abscesses or masses under the breast.
    • Granulomatous mastitis: A rare inflammatory condition of the breast tissue that can cause soreness and other symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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