2022 Difficult Airway Management Guidelines
The 2022 difficult airway management guidelines emphasize using videolaryngoscopy as the first-line approach for patients with suspected or confirmed difficult airways, with a structured algorithm for rescue techniques when initial attempts fail. 1
Airway Assessment and Prediction
Key Assessment Components:
- Predictors of difficult direct laryngoscopy:
- Modified Mallampati classification (Class 3-4 correlates with Cormack-Lehane Grade 2-4) 2
- Thyromental distance (highest sensitivity and negative predictive value) 3
- Upper lip bite test (highest specificity) 3
- Inter-incisor gap
- Atlantooccipital extension
- LEMON assessment (Look, Evaluate, Mallampati, Obstruction, Neck mobility)
Risk Stratification:
- Multiple attempts at tracheal intubation increase patient morbidity 4
- When difficulty is anticipated, limit attempts to maximum of three with any chosen device 4
- Consider awake approach when multiple aspects of airway management are predicted to be difficult 5
Management Algorithm for Difficult Airways
First-Line Approach:
- Videolaryngoscopy is recommended as first-line for patients with suspected or confirmed difficult airways (Grade A; moderate recommendation) 1
- No specific videolaryngoscope type or blade is recommended over others 1
- Regular training with videolaryngoscopy in simulated difficult airway scenarios is essential 1
Airway Techniques:
For basic airway maneuvers:
For supraglottic airway devices (SADs):
For predicted difficult intubation:
- Consider awake tracheal intubation when:
- Impossible videolaryngoscopy or direct laryngoscopy is predicted
- Multiple modes of airway management are predicted to be difficult
- Physiological or contextual issues increase risk 5
- Consider awake tracheal intubation when:
Rescue Techniques:
If initial intubation fails:
- Transition through algorithm promptly
- Declare difficulty to the team at each stage
- Consider second-generation SAD between attempts (better seal, less aerosol generation) 1
Cannot Intubate, Cannot Oxygenate (CICO) scenario:
Post-Intubation Management
After successful intubation:
Ongoing management:
Common Pitfalls and Caveats
- Overreliance on single predictors: No single airway test provides high sensitivity and specificity; combine multiple tests 3
- Delayed recognition of failure: Define clear triggers for moving from one technique to the next 5
- Inadequate preparation: Ensure difficult airway equipment is readily available before induction 5
- Failure to anticipate: Preoperative anticipation of difficult airways occurs in only 50% of cases; always have a backup plan 6
- Extubation risks: Carefully plan extubation of at-risk patients, including assessment of tolerance for airway support withdrawal 5
The guidelines emphasize that while prediction tools are helpful, unanticipated difficulty can always occur, necessitating a prepared strategy for every patient and institutional readiness with appropriate equipment.