Protocol for Drawing Potassium Lab via PICC Line
When drawing blood samples for potassium measurement from a PICC line, proper technique must be followed to ensure accurate results and prevent complications.
Proper Blood Draw Technique for PICC Lines
Preparation Steps
Gather all necessary supplies:
- Sterile gloves
- Chlorhexidine solution with alcohol for site preparation 1
- Appropriate blood collection tubes
- Syringes (10-20 mL for discard sample, appropriate size for actual draw)
- Normal saline flush solution
- Sterile caps/connectors
Perform hand hygiene and don sterile gloves 1
Prepare the PICC hub:
- Disinfect the hub with chlorhexidine solution with alcohol 1
- Allow the hub to dry completely before accessing (critical for preventing contamination)
Blood Drawing Procedure
Always draw a discard sample first (5-10 mL) to clear the line of any medications, parenteral nutrition, or heparin that could affect potassium results 1
After obtaining the discard sample:
- Disconnect that syringe
- Connect a new sterile syringe for the actual blood sample
- Draw the required amount for potassium testing (typically 3-5 mL)
Transfer the blood sample to appropriate collection tubes immediately
Post-draw maintenance:
- Flush the PICC line with 10-20 mL of normal saline 1
- Resume any infusions that were temporarily stopped
Important Considerations
Preventing False Results
- Hemolysis can falsely elevate potassium levels - avoid excessive suction pressure when drawing samples
- If the PICC was used for parenteral nutrition, ensure adequate discard volume is drawn 1
- For patients receiving multiple incompatible infusions through a multi-lumen PICC, use the dedicated lumen for blood sampling 1
Line Maintenance
- Weekly flushing is recommended for PICC lines not in active use 1
- Use normal saline rather than heparin to maintain catheter patency 1
- Ensure proper documentation of the blood draw procedure
Contraindications and Special Populations
- For patients with chronic kidney disease stage 3b or worse (eGFR <45 mL/min), consider alternative access methods as preservation of upper extremity veins is critical 1, 2
- In patients receiving home parenteral nutrition, PICC lines may not be recommended for long-term use 1
Troubleshooting
If difficulty obtaining blood return:
- Reposition the patient's arm
- Have patient perform Valsalva maneuver
- Consider a small (3-5 mL) normal saline flush if absolutely necessary, but this may affect lab results
- Never forcefully flush a resistant PICC line
Following this protocol will help ensure accurate potassium results while maintaining the integrity of the PICC line and preventing complications such as infection or catheter occlusion.