Angioedema: This condition is characterized by the rapid swelling of the dermis, subcutaneous tissue, mucosa, and submucosal tissues. It can be caused by allergic reactions, often presenting with GI symptoms and lip swelling without necessarily involving the respiratory system.

Food Allergy: An allergic reaction to certain foods can cause GI symptoms and lip swelling. Common culprits include nuts, shellfish, milk, eggs, fish, soy, and wheat.
Eosinophilic Gastroenteritis: A condition where eosinophils infiltrate the gastrointestinal tract, leading to GI symptoms. It can be associated with food allergies or atopic diseases and may present with lip swelling due to systemic involvement.
Insect Sting Allergy: Similar to food allergies, an allergic reaction to an insect sting can cause localized or generalized symptoms, including GI issues and lip swelling.

Hereditary Angioedema (HAE): A rare but potentially life-threatening condition characterized by recurrent episodes of severe angioedema. It's crucial to identify HAE due to its implications for treatment and the risk of airway obstruction, even though respiratory issues are not currently present.
Anaphylaxis: Although the question specifies no respiratory issues, anaphylaxis can present with a wide range of symptoms, including GI issues and lip swelling. It's a medical emergency that requires immediate attention.

Mastocytosis: A condition where there's an accumulation of mast cells in one or more organs. It can cause a variety of symptoms, including GI issues and swelling, due to the release of histamine and other mediators from mast cells.
Eosinophilic Esophagitis: While primarily affecting the esophagus, it can be part of a broader eosinophilic gastrointestinal disorder. Symptoms might include difficulty swallowing, food impaction, and potentially systemic symptoms like lip swelling in severe cases.