Duration of Peripherally Inserted Central Catheters (PICCs)
The appropriate duration of a PICC line is typically 15 days to 3 months, with removal recommended when the device is no longer clinically necessary. 1
Duration Guidelines Based on Clinical Context
General Medical Patients
- Short-term use (1-3 weeks): PICCs are inappropriate for peripherally compatible infusions unless treatment duration exceeds 15 days 1
- Intermediate use (<3 months): PICCs are appropriate for continuous or intermittent infusion therapies lasting up to 3 months 1
- Long-term use (>3 months): Consider transitioning to tunneled catheters or ports for therapy expected to last longer than 3 months 1
Specific Clinical Scenarios
Cancer Patients
- Non-irritant/non-vesicant chemotherapy: PICCs appropriate only if treatment duration is 3 months or less 1
- Irritant/vesicant chemotherapy: PICCs appropriate at all time intervals 1
- Frequent phlebotomy/difficult access: PICCs appropriate only if duration exceeds 15 days 1
- Long-term therapy: For treatments >6 months, ports are preferred over PICCs 1
Critical Care Patients
- Hemodynamically stable: PICCs inappropriate unless treatment exceeds 15 days 1
- Hemodynamically unstable: PICCs appropriate only for durations of 15+ days (CVCs preferred for shorter durations) 1
- Coagulopathies: PICCs preferred over CVCs when use exceeds 15 days 1
Patients Requiring Lifelong Access
- Infrequent hospitalizations (<5/year): PICCs appropriate only if duration exceeds 15 days 1
- Frequent hospitalizations (≥6/year): Tunneled catheters preferred over PICCs for durations ≥15 days 1
Complications Affecting Duration
PICCs may require early removal due to complications, which occur in approximately 27% of cases 2:
- Mechanical complications: Obstruction (13.5%) and accidental removal (9.6%) 3
- Infectious complications: 3.8% in oncology patients 3, with higher risk as duration increases
- Thrombotic complications: Venous thrombosis occurs in approximately 8% of cases 2
When to Remove a PICC
PICCs should be removed when 1:
- Not used for clinical purposes for 48+ hours
- Original indication has been met (e.g., antibiotic course completed)
- Only being used for routine blood samples in stable patients with available peripheral veins
Practical Considerations
- The median duration of PICC use varies by indication: 26 days overall, with longer durations (median 58 days) for chemotherapy 3
- Frequent blood sampling (>2/week) is associated with shorter PICC duration (median 23 days) due to increased complications 3
- In post-hematopoietic stem cell transplant patients, PICCs have been used safely with a median duration of 67 days 2
Common Pitfalls to Avoid
- Leaving PICCs in place too long: Remove when no longer needed to reduce infection risk
- Using PICCs for short-term therapy: For durations <15 days, peripheral IVs or midline catheters are generally more appropriate 1
- Inappropriate device selection: Consider patient-specific factors and expected duration of therapy when choosing between PICC, tunneled catheter, or port
- Inadequate patient education: Proper education about PICC care can prevent complications and extend device lifespan 4
Remember that while these guidelines provide general recommendations, the actual duration of a PICC depends on ongoing assessment of its necessity, function, and absence of complications.