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Differential Diagnosis for Dark Square Spot on Lower Back

  • Single most likely diagnosis
    • Melanocytic nevus (mole): A common, benign skin lesion that can appear as a dark spot, often round or oval but can sometimes appear square due to the skin's surface characteristics or the way the lesion grows.
  • Other Likely diagnoses
    • Seborrheic keratosis: A benign skin growth that can appear as a dark, wart-like spot and can sometimes have a square shape due to its growth pattern.
    • Dermatofibroma: A small, round or oval growth that can appear after a minor injury, sometimes presenting as a dark spot, though less commonly square.
    • Cafe-au-lait macule: A benign skin patch that can be darker than the surrounding skin, though typically lighter than a melanocytic nevus and can vary in shape.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed)
    • Melanoma: Although less common, a new or changing dark spot, especially one that is asymmetric, has irregular borders, color variation, diameter larger than 6mm, or is evolving, could be a sign of skin cancer.
    • Metastatic lesion: In rare cases, a dark spot could be a metastasis from an internal malignancy, which would be critical to identify early.
  • Rare diagnoses
    • Blue nevus: A type of melanocytic nevus that can appear more blue or black due to the depth of the melanin in the skin, and while typically round, could appear square.
    • Mongolian spot: A congenital melanocytic lesion that appears as a blue or blue-gray flat spot, most common in infants, which can sometimes appear on the lower back and may fade with age.
    • Tattoo or pigment implantation: Though not a medical condition per se, a dark square spot could be due to intentional or accidental tattooing or pigment implantation in the skin.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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