Essential Information for Radiologists Before MRI with Contrast
Before performing an MRI with contrast, radiologists need to know about metallic implants, pregnancy status, and history of allergic reactions to gadolinium-based contrast agents, in addition to renal function and liver disease. 1
Patient Information Required Before MRI with Contrast
Medical History
- Renal function status: eGFR measurement is critical, especially if < 30 ml/min/1.73m² 1
- Liver disease: Important for contrast metabolism and clearance 1
- Allergies: History of previous reactions to gadolinium-based contrast agents 1
- Pregnancy status: Gadolinium is not recommended in pregnancy unless absolutely necessary 1
- Metallic implants: Complete screening for all implanted devices 1
- Recent treatments: Minimum delay of 1 month after radiotherapy/surgery to reduce false positives from inflammation 1
Implant Information
- Detailed implant information: Type, location, material, and MRI compatibility status 1
- Implant classification: MRI unsafe (absolute contraindication), MRI conditional (relative contraindication with specific conditions), or MRI safe (no contraindication) 1
- Special devices: Neurostimulators, baclofen pumps, analgesic pumps, or intracranial pressure monitors require special consideration 1
- Biohacking implants: Self-implanted technological enhancements like fingertip magnets or RF identification chips 1
Patient Preparation
- Body weight: Must be documented for accurate contrast dosing 1
- Removal of metallic items: Jewelry, dental prostheses, clothing with metal components 1
- Hearing protection: Required due to loud acoustic noise during scanning 1
- Patient positioning ability: Patient must be able to lie still for the duration of the scan 1
Contrast-Related Considerations
Gadolinium Safety
- Risk of nephrogenic systemic fibrosis (NSF): Particularly in patients with eGFR < 30 ml/min/1.73m² 1
- Contrast agent selection: Macrocyclic gadolinium compounds bind gadolinium more tightly and have not been associated with NSF 1
- Contrast dosing: Minimal dose should be used in patients with renal insufficiency 1
- Timing of repeat administration: Should not be repeated within 7 days in patients with low GFR 1
Allergic Reactions
- Incidence of severe anaphylactoid reactions: Up to 0.01% 1
- Common mild side effects: Headaches, nausea, dizziness (1-5% of cases) 1
Common Pitfalls and Caveats
Implant compatibility verification: Always verify MRI compatibility of implants before scanning - don't rely solely on patient reports 1
Gadolinium in renal insufficiency: Using older linear gadolinium compounds in patients with severe renal impairment can lead to NSF; newer macrocyclic agents are preferred 1
Contrast timing after treatments: Scanning too soon after radiotherapy or surgery can lead to false positive results due to inflammation 1
Baclofen pump safety: There have been incidents where the entire dose of a baclofen pump was discharged during scanning 1
Artifact considerations: Implants can cause significant signal voids and geometric distortions in MRI images, potentially complicating interpretation 1
By ensuring all these factors are assessed before performing an MRI with contrast, radiologists can maximize diagnostic quality while minimizing risks to patients.