Differential Diagnosis for Hypertension in a 52-year-old Female with DM and Knee Osteoarthritis
- Single most likely diagnosis
- C. NSAIDs induced HTN: The patient has been using NSAIDs to relieve her pain, which is a well-known cause of secondary hypertension due to its effect on renal function and fluid balance, particularly in patients with pre-existing conditions like diabetes mellitus.
- Other Likely diagnoses
- A. Essential HTN: Given the patient's age and the presence of diabetes mellitus, essential hypertension is a common condition that could coexist or be exacerbated by other factors.
- D. Primary hyperaldosteronism: The low borderline potassium level (hypokalemia) could suggest primary hyperaldosteronism, a condition where excess aldosterone leads to hypertension and hypokalemia.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- B. Pheochromocytoma: Although less likely, pheochromocytoma is a critical diagnosis not to miss due to its potential for severe, life-threatening hypertension. However, it typically presents with episodic hypertension, headaches, sweating, and tachycardia, which are not mentioned in the scenario.
- Rare diagnoses
- Other rare causes of secondary hypertension, such as Cushing's syndrome, hyperthyroidism, or renal artery stenosis, could be considered but are less likely given the information provided. These conditions often have additional specific symptoms or signs that are not described in the scenario.