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Last updated: July 12, 2025View editorial policy

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Differential Diagnosis for a 24-year-old Lady with a Hard, Mobile, Well-circumscribed Painless Left Breast Mass

  • Single most likely diagnosis
    • B. Fibroadenoma: This is the most likely diagnosis due to the characteristics of the mass being hard, mobile, well-circumscribed, and painless, which are classic features of fibroadenomas. Fibroadenomas are common benign breast tumors, especially in young women, and they can grow over time without being related to the menstrual cycle.
  • Other Likely diagnoses
    • A. Fat cyst (traumatic fat necrosis): Although less likely than fibroadenoma, a fat cyst could present as a hard, mobile mass. However, it is usually associated with a history of trauma, which is not mentioned in the scenario.
    • C. Fibrocystic changes: These changes can cause lumps in the breast, but they are typically multiple, bilateral, and fluctuate with the menstrual cycle, which does not perfectly match the description provided.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed)
    • Breast Cancer (not listed among the options): Although the presentation is atypical for breast cancer (especially given the patient's age and the description of the mass), it is crucial not to miss this diagnosis. Breast cancer can present as a hard, mobile mass, and it's essential to consider it, especially if there's any deviation from the expected clinical course or if imaging and biopsy results suggest malignancy.
  • Rare diagnoses
    • D. Intraductal papilloma (difficult to palpate): Intraductal papillomas are usually small and not palpable, presenting more commonly with nipple discharge. They are less likely to be the correct diagnosis given the description of a hard, mobile, well-circumscribed mass.
    • Phyllodes Tumor: Although not listed, phyllodes tumors can present similarly to fibroadenomas but are less common. They can be benign, borderline, or malignant, making them an important consideration in the differential diagnosis of a breast mass, especially if it grows rapidly.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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