Recommended Dosage of Diclofenac (Rofinac) Suppository for Babies
For babies requiring diclofenac (Rofinac) suppositories, the recommended dose is 1-3 mg/kg per dose, with a maximum of 50 mg per dose.
Dosing Considerations
Diclofenac suppositories should be used cautiously in infants due to limited safety data specifically for this age group. When administering:
- For infants under 1 year: 1-2 mg/kg per dose
- For children 1-12 years: 1-3 mg/kg per dose
- Maximum frequency: 2-3 times daily
- Do not exceed maximum daily dose of 3 mg/kg/day
Important Safety Considerations
Contraindications
- History of NSAID hypersensitivity
- Active gastrointestinal bleeding
- Severe renal impairment
- Dehydration
Monitoring
- Watch for signs of gastrointestinal irritation
- Monitor for changes in urine output
- Assess for any allergic reactions
Alternative Options
For fever and pain management in infants, consider these alternatives if appropriate:
- Acetaminophen (paracetamol): 10-15 mg/kg per dose every 4-6 hours
- Ibuprofen suppositories (for infants >3 months): 5-10 mg/kg per dose
Clinical Pearls
- Diclofenac suppositories should be used for the shortest duration possible to minimize adverse effects
- Rectal administration may be preferred when oral administration is difficult or contraindicated
- NSAIDs like diclofenac should be avoided in dehydrated infants due to increased risk of renal adverse effects
- Consider using after meals to reduce gastrointestinal side effects
Common Pitfalls to Avoid
- Avoid concurrent use with other NSAIDs
- Do not use in infants with suspected or confirmed cardiac disease without specialist consultation
- Avoid prolonged use (>3 days) without medical supervision
- Do not split suppositories as this may lead to inaccurate dosing
Always reassess the need for continued treatment after 24-48 hours and discontinue as soon as symptoms are controlled.