What are common signs of illness in pets?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: July 13, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Common Signs of Illness in Pets

Recognizing signs of illness in pets is critical for early intervention, as pets cannot verbally communicate their discomfort and many illnesses can progress rapidly if left untreated. Based on the available guidelines, several common signs may indicate that a pet is ill and requires veterinary attention.

General Signs of Illness in Pets

Behavioral Changes

  • Lethargy or decreased activity level
  • Decreased appetite or complete anorexia
  • Changes in temperament (increased aggression or withdrawal)
  • Confusion or disorientation
  • Tremors

Physical Signs

  • Fever (elevated body temperature)
  • Vomiting
  • Diarrhea (watery or bloody)
  • Weight loss
  • Scleral injection (redness in the whites of the eyes)
  • Skin abnormalities including rashes or petechial lesions on mucous membranes 1

Disease-Specific Signs

Gastrointestinal Disorders

  • Persistent vomiting
  • Diarrhea (may be watery or contain blood)
  • Weight loss despite normal or increased appetite
  • Increased frequency of defecation
  • Straining to defecate 2, 3

In dogs with chronic enteropathy, vomiting without diarrhea is present in approximately 27% of cases 4. Following episodes of acute hemorrhagic diarrhea, dogs have a higher risk (28% vs 13% in controls) of developing signs of chronic gastrointestinal disease 5.

Tickborne Diseases

Pets, particularly dogs, can develop tickborne diseases that present with:

  • Fever
  • Lethargy
  • Decreased appetite
  • Tremors
  • Scleral injection
  • Maculopapular rash on ears and exposed skin
  • Petechial lesions on mucous membranes 1

It's important to note that dogs can serve as sentinels for tickborne diseases that also affect humans. Documentation of tickborne rickettsial disease in a dog should prompt awareness of potential risk to human household members 1.

When to Seek Veterinary Care

Immediate veterinary attention is warranted when pets show:

  • Changes in mental status (confusion, lethargy)
  • Persistent fever
  • Inability to keep food or water down
  • Bloody diarrhea
  • Collapse or severe weakness
  • Difficulty breathing

Important Considerations

Pet-Human Disease Connection

  • Dogs and humans can be susceptible to the same tickborne pathogens, including Rickettsia rickettsii, Ehrlichia chaffeensis, Ehrlichia ewingii, and Anaplasma phagocytophilum 1
  • Clustering of certain diseases can occur among family members and their pets 1
  • A pet's illness may precede and indicate risk for human illness in the household 1

Diagnostic Challenges

  • Many illnesses in pets present with nonspecific signs initially
  • Laboratory abnormalities like leukopenia (decreased white blood cells) and thrombocytopenia (decreased platelets) may indicate serious infections 1
  • Chronic conditions like inflammatory bowel disease may require specialized diagnostics including endoscopy and biopsy 6

Monitoring Progression

Pet owners should monitor:

  • Duration of symptoms
  • Progression or worsening of signs
  • Response to any treatments
  • Changes in eating, drinking, urination, and defecation patterns

Early recognition of these signs and prompt veterinary care can significantly improve outcomes and prevent serious complications or death in pets with illness.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Idiopathic inflammatory bowel disease in dogs and cats: 84 cases (1987-1990).

Journal of the American Veterinary Medical Association, 1992

Research

Inflammatory bowel disease in veterinary medicine.

Frontiers in bioscience (Elite edition), 2012

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.