Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: July 13, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Persistent Vaginal Itching

Single Most Likely Diagnosis

  • Vulvovaginal Candidiasis: This is the most common cause of vaginal itching, especially in women of reproductive age. It is caused by an overgrowth of Candida albicans, a fungus that is normally present in the vagina. Symptoms include intense itching, redness, and a thick, white discharge.

Other Likely Diagnoses

  • Bacterial Vaginosis (BV): BV is a bacterial infection that occurs when the normal balance of bacteria in the vagina is disrupted. It can cause vaginal itching, burning, and a fishy-smelling discharge.
  • Vaginal Atrophy: This condition occurs when the vaginal walls become thin and dry, often due to decreased estrogen levels during menopause. It can cause vaginal itching, burning, and pain during sex.
  • Contact Dermatitis: This is a skin reaction that can occur when the vulva comes into contact with an irritant, such as soap, detergent, or fabric softener. It can cause vaginal itching, redness, and burning.

Do Not Miss Diagnoses

  • Lichen Sclerosus: This is a rare skin condition that can cause vaginal itching, pain, and scarring. If left untreated, it can increase the risk of vulvar cancer.
  • Vulvar Cancer: This is a rare type of cancer that can cause vaginal itching, pain, and bleeding. It is often diagnosed at an advanced stage, making it important to rule out in women with persistent vaginal itching.
  • Herpes Simplex Virus (HSV): HSV is a viral infection that can cause vaginal itching, pain, and blisters. It can be transmitted through sexual contact and can have serious consequences if left untreated.

Rare Diagnoses

  • Vulvar Intraepithelial Neoplasia (VIN): This is a rare precancerous condition that can cause vaginal itching, pain, and abnormal cell growth.
  • Desquamative Inflammatory Vaginitis (DIV): This is a rare condition that can cause vaginal itching, burning, and a thick, yellow discharge.
  • Allergic Reactions: Rarely, vaginal itching can be caused by an allergic reaction to certain medications, such as antibiotics or antifungals.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.