What is the recommended dose of ibuprofen (nonsteroidal anti-inflammatory drug) for an individual weighing 82 pounds?

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Recommended Ibuprofen Dosage for an 82-Pound Individual

For a child weighing 82 pounds (approximately 37 kg), the recommended dosage of ibuprofen is 10-15 mg/kg every 6-8 hours, which equals approximately 370-555 mg per dose, not to exceed 2,400 mg per day. 1

Dosage Calculation

Based on the most recent guidelines, the appropriate dosage can be determined as follows:

  • Weight: 82 pounds = approximately 37 kg
  • For children weighing 23-40 kg, the recommended dosage is 60 mg per dose 1
  • For children weighing more than 40 kg (88 lb), the recommended dosage is 75 mg per dose 1

Since 82 pounds (37 kg) is very close to the 40 kg threshold, the appropriate dosage would be:

  • 10-15 mg/kg per dose = 370-555 mg per dose
  • Practically, this would be rounded to 400 mg per dose (standard tablet/capsule size)

Administration Schedule

  • Take every 6-8 hours as needed for pain or fever
  • Do not exceed 4 doses in 24 hours
  • Maximum daily dose should not exceed 2,400 mg per day

Formulation Options

  • Tablets/capsules: 200 mg or 400 mg (2 × 200 mg tablets would be appropriate)
  • Liquid suspension: Available in various concentrations (check specific product for dosing)

Important Considerations

Safety Precautions

  • Duration: For over-the-counter use, do not use for more than 10 days without consulting a healthcare provider
  • Take with food: Ibuprofen should be taken with food to minimize gastrointestinal side effects 2
  • Hydration: Ensure adequate hydration while taking ibuprofen

Potential Side Effects

  • Gastrointestinal effects: Nausea, stomach pain, heartburn
  • Risk of GI bleeding increases with higher doses and prolonged use
  • Renal effects: Particularly with dehydration or pre-existing kidney disease

Contraindications

  • Allergy to NSAIDs
  • History of GI bleeding or ulcers
  • Severe heart failure
  • Third trimester of pregnancy
  • Concurrent use with other NSAIDs

Special Populations

For individuals with underlying health conditions:

  • Hepatic impairment: Use with caution and consider dose reduction
  • Renal impairment: Avoid if possible, especially with creatinine clearance <30 mL/min
  • Cardiovascular disease: Use lowest effective dose for shortest duration

Clinical Pearls

  • Ibuprofen has been shown to be more effective than acetaminophen (paracetamol) for inflammatory conditions 2
  • The analgesic effect of ibuprofen 400 mg lasts approximately 6 hours compared to 4-6 hours for ibuprofen 200 mg 3
  • For fever reduction, ibuprofen may be more effective than acetaminophen in some cases

Remember that this dosing is based on weight and not age, which provides a more accurate dosage for optimal therapeutic effect while minimizing potential adverse effects.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Ibuprofen: pharmacology, efficacy and safety.

Inflammopharmacology, 2009

Research

Review of the analgesic efficacy of ibuprofen.

International journal of clinical practice. Supplement, 2003

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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