From the Research
Hyperhidrosis treatment should begin with antiperspirants containing aluminum chloride, and may progress to iontophoresis, botulinum toxin injections, or oral anticholinergics for more severe cases, as these treatments have been shown to improve quality of life and reduce morbidity 1. The treatment of hyperhidrosis depends on the severity and location of the condition, and a stepwise approach is often recommended.
- Initial treatment typically involves lifestyle modifications, such as wearing breathable fabrics and avoiding spicy foods and caffeine, to reduce triggers that worsen sweating.
- Topical antiperspirants, such as aluminum chloride, are often the first-line treatment for primary focal hyperhidrosis, and can provide significant benefit 2.
- Iontophoresis, which uses a mild electrical current to temporarily block sweat glands, is effective for hands and feet, and can be used in conjunction with other treatments 3.
- Botulinum toxin injections can provide 4-6 months of relief for underarms, hands, and feet, and are considered a safe and effective treatment option for focal hyperhidrosis 2.
- Oral anticholinergics, such as glycopyrrolate or oxybutynin, can reduce sweating throughout the body, but may cause side effects such as dry mouth and blurred vision 4.
- For severe cases unresponsive to other treatments, microwave thermolysis or sympathectomy surgery may be considered, although these options carry risks and should be carefully weighed against potential benefits 5. It is essential to consider the potential risks and benefits of each treatment option and to individualize treatment based on the patient's specific needs and circumstances, prioritizing morbidity, mortality, and quality of life as the primary outcomes 1.