Viral Hepatitis: This is often the most common cause of elevated liver enzymes in children, with hepatitis A being particularly prevalent in this age group due to its highly contagious nature and the fact that many children have not yet been vaccinated against it.

Non-Alcoholic Fatty Liver Disease (NAFLD): Although more commonly associated with adults, NAFLD is increasingly recognized in children, especially those who are overweight or obese. It can lead to elevated liver enzymes.
Medication-Induced Liver Injury: Various medications, including certain antibiotics and anticonvulsants, can cause liver enzyme elevations as a side effect.
Autoimmune Hepatitis: An autoimmune condition where the body's immune system attacks liver cells, leading to inflammation and elevated liver enzymes.

Wilson's Disease: A genetic disorder that leads to copper accumulation in the liver, causing damage. It's crucial to diagnose early to prevent irreversible liver damage and neurological symptoms.
Alpha-1 Antitrypsin Deficiency: A genetic disorder that can cause liver disease and lung disease. Early diagnosis is critical for managing the condition and preventing complications.
Acute Liver Failure: Conditions such as acetaminophen overdose or other toxic ingestions can lead to rapid deterioration of liver function, requiring immediate medical attention.

Glycogen Storage Diseases: A group of genetic disorders that affect the body's ability to store glycogen, leading to various systemic and liver-related symptoms.
Cystic Fibrosis: While primarily known for its respiratory symptoms, cystic fibrosis can also affect the liver, leading to focal biliary cirrhosis and multilobular cirrhosis.
Budd-Chiari Syndrome: A rare condition caused by obstruction of the hepatic veins, leading to liver enlargement, ascites, and abdominal pain.
Schistosomiasis: A parasitic infection that can cause liver fibrosis and is more common in certain geographic regions.