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Differential Diagnosis for 73 F with hx of HTN, anxiety, HLD

Single Most Likely Diagnosis

  • Chronic Hydrochlorothiazide-induced Hypokalemia and Mild Anemia: The patient's lab results show low sodium (134 mmol/L) and low potassium (4.2 mmol/L) levels, which could be attributed to hydrochlorothiazide use. The mild anemia (Hemoglobin 12.1 g/dL) could be related to chronic disease or medication side effects.

Other Likely Diagnoses

  • Viral Infection: The patient's low neutrophil count (26.4%) and high lymphocyte count (63.9%) could indicate a viral infection.
  • Medication-induced Leukopenia: The patient's low white blood cell count (4.5 K/mcL) could be a side effect of Zoloft or other medications.
  • Chronic Kidney Disease: Although the patient's eGFR is within normal limits (92 mL/min/1.73m2), the high BUN/Creatinine Ratio (20.3) could indicate early kidney disease.

Do Not Miss Diagnoses

  • Sepsis: Although the patient's vital signs are not provided, the low neutrophil count and high lymphocyte count could indicate a severe infection. Sepsis is a life-threatening condition that requires prompt diagnosis and treatment.
  • Leukemia or Lymphoma: The patient's abnormal white blood cell count and differential could indicate a hematologic malignancy.
  • Adrenal Insufficiency: The patient's low sodium and potassium levels could be indicative of adrenal insufficiency, which is a life-threatening condition if left untreated.

Rare Diagnoses

  • Felty's Syndrome: The patient's rheumatoid arthritis (not mentioned in the history, but possible) and abnormal white blood cell count could indicate Felty's syndrome, a rare condition characterized by rheumatoid arthritis, splenomegaly, and neutropenia.
  • Pernicious Anemia: The patient's mild anemia could be related to pernicious anemia, a rare condition caused by vitamin B12 deficiency.
  • Myelodysplastic Syndrome: The patient's abnormal white blood cell count and differential could indicate myelodysplastic syndrome, a rare group of disorders characterized by bone marrow failure.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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