How effective is liposuction of axillary (underarm) sweat glands in treating hyperhidrosis (excessive sweating)?

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Effectiveness of Liposuction for Axillary Hyperhidrosis

Liposuction-curettage of axillary sweat glands is highly effective for treating hyperhidrosis, with studies showing 76-89% excellent or good results and sweat reduction rates of up to 69% in patients. 1, 2

Mechanism and Technique

Liposuction-curettage works by:

  • Physically removing or destroying both apocrine and eccrine sweat glands in the axillary region
  • Using tumescent local anesthesia (typically lidocaine with epinephrine) for the procedure
  • Often employing specialized cannulas like the Fatemi cannula for effective gland removal 1

Efficacy Data

The evidence strongly supports the effectiveness of this approach:

  • In a study of 25 patients (50 axillae), 76% achieved excellent results and 22% good results 1
  • Even for patients who didn't respond adequately to initial liposuction-curettage, a second procedure with an aggressive rasping cannula provided 69% sweat reduction in 89% of patients 2
  • Quality of life improvements are significant, with 91% of patients reporting satisfaction after the procedure 3

Procedural Considerations

For optimal results, the procedure should include:

  • Tumescent local anesthesia using lidocaine with epinephrine (maximum safe dose 55 mg/kg for patients weighing 43.6-81.8 kg) 4
  • Warm anesthetic solution and slow infiltration rate to decrease patient discomfort during administration 4
  • Starch-iodine testing to delineate the hyperhidrotic areas before and after the procedure 5
  • Curettage in addition to liposuction for more complete removal of sweat glands 1

Advantages Over Other Treatments

Compared to other treatment options:

  • More permanent solution than botulinum toxin injections, which require repeated treatments
  • Less scarring compared to radical surgical excision methods
  • Fewer complications than more invasive surgical approaches like sympathectomy
  • One-time procedure versus ongoing medical therapy

Potential Complications and Limitations

The procedure is generally safe with minimal complications:

  • Temporary ecchymosis (bruising)
  • Minor local infections in some cases
  • No severe side effects reported in the studies reviewed 1, 2
  • Excellent aesthetic outcomes with minimal scarring (mean Vancouver Scar Scale 1.1 after surgery) 2

Alternative Options

For patients who may not be candidates for liposuction-curettage:

  • Botulinum toxin injections (effective but temporary)
  • Newer microwave energy thermolysis (minimally invasive) 6
  • For palmar hyperhidrosis, wrist nerve blocks have shown efficacy 4

Follow-up Care

Post-procedure care should include:

  • Regular application of bland emollients to prevent dryness
  • Monitoring for any signs of infection
  • Assessment of treatment efficacy through patient satisfaction and potentially repeat gravimetry

Liposuction-curettage represents a safe, effective, and relatively permanent solution for axillary hyperhidrosis with high patient satisfaction rates and minimal complications.

References

Research

Tumescent liposuction with dermal curettage for treatment of axillary osmidrosis and hyperhidrosis.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2006

Research

[Liposuction curettage versus Botox for axillary hyperhidrosis. A prospective study of the quality of life].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2007

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Treatment of axillary hyperhidrosis: combination of the starch-iodine test with the tumescent liposuction technique.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2000

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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