What are the current guidelines for managing cardiac arrest according to the American Heart Association (AHA), Heart and Stroke, and European Resuscitation Council (ERC)?

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Last updated: July 17, 2025View editorial policy

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Current Guidelines for Managing Cardiac Arrest According to AHA, Heart and Stroke, and ERC

The immediate provision of high-quality cardiopulmonary resuscitation (CPR) combined with rapid defibrillation (when appropriate) forms the foundation of cardiac arrest management according to the American Heart Association (AHA) guidelines. 1

Recognition of Cardiac Arrest

  • For lay rescuers: Assume cardiac arrest if a victim is unconscious/unresponsive with absent or abnormal breathing (i.e., only gasping) 1
  • For healthcare providers: Check for a pulse for no more than 10 seconds; if no definite pulse is felt, assume cardiac arrest 1

High-Quality CPR Components

  • Chest Compressions:

    • Depth: At least 2 inches (5 cm) but avoid exceeding 2.4 inches (6 cm) 1
    • Rate: 100-120 compressions per minute 1
    • Allow complete chest recoil between compressions 1
    • Minimize interruptions in compressions 1
    • Change compressor every 2 minutes, or sooner if fatigued 1
  • Ventilation:

    • Avoid excessive ventilation 1
    • After advanced airway placement: 1 breath every 6 seconds (10 breaths/minute) with continuous chest compressions 1

Adult Cardiac Arrest Algorithm

For Shockable Rhythms (VF/pVT):

  1. Begin CPR immediately
  2. Apply AED/defibrillator as soon as available
  3. Deliver shock if VF/pVT
  4. Resume CPR immediately for 2 minutes
  5. Check rhythm
  6. Continue cycles of shock → CPR → rhythm check
  7. Establish IV/IO access
  8. Administer epinephrine every 3-5 minutes
  9. Consider advanced airway
  10. Consider antiarrhythmic medications for refractory VF/pVT:
    • Amiodarone: First dose 300 mg IV/IO, second dose 150 mg IV/IO
    • Lidocaine: First dose 1-1.5 mg/kg IV/IO, second dose 0.5-0.75 mg/kg IV/IO 1

For Non-Shockable Rhythms (PEA/Asystole):

  1. Begin CPR immediately
  2. Check rhythm every 2 minutes
  3. Establish IV/IO access
  4. Administer epinephrine as soon as feasible, then every 3-5 minutes 1
  5. Consider advanced airway
  6. Identify and treat reversible causes 1

Medication Administration

  • Epinephrine:

    • Standard dose: 1 mg IV/IO every 3-5 minutes 1
    • For non-shockable rhythms: Administer as soon as feasible 1
    • For shockable rhythms: After initial defibrillation attempts 1
    • High-dose epinephrine is not recommended 1
  • Vascular Access:

    • It is reasonable to first attempt establishing IV access for drug administration 1
    • IO access may be considered if attempts at IV access are unsuccessful or not feasible 1

Advanced Airway Management

  • Either bag-mask ventilation or an advanced airway may be used during CPR 1
  • For healthcare providers trained in their use, either a supraglottic airway (SGA) device or an endotracheal tube (ETT) may be used as the initial advanced airway 1
  • Continuous waveform capnography is recommended to confirm and monitor correct ETT placement 1

Post-Resuscitation Care

After Return of Spontaneous Circulation (ROSC):

  • Initiate post-cardiac arrest care
  • Monitor for recurrent cardiac arrest
  • Assess for reversible causes
  • Consider targeted temperature management
  • Consider cardiac catheterization when indicated 1

Reversible Causes (H's and T's)

  • Hypovolemia
  • Hypoxia
  • Hydrogen ion (acidosis)
  • Hypo-/hyperkalemia
  • Hypothermia
  • Tension pneumothorax
  • Tamponade, cardiac
  • Toxins
  • Thrombosis, pulmonary
  • Thrombosis, coronary 1

Special Considerations

Extracorporeal CPR (ECPR)

  • May be considered for select patients with potentially reversible causes of cardiac arrest 1
  • Shows promise for cardiac arrest due to massive pulmonary embolism, with studies showing improved survival with favorable neurological outcomes compared to conventional CPR (21% vs 0%) 2

Mechanical CPR Devices

  • Manual chest compressions remain the standard of care 1
  • Mechanical devices may be reasonable in specific settings where high-quality manual compressions are challenging (e.g., prolonged CPR, moving ambulance, angiography suite) 1

Common Pitfalls to Avoid

  1. Delayed CPR initiation: Begin compressions immediately upon recognition of cardiac arrest
  2. Prolonged pulse checks: Limit to no more than 10 seconds
  3. Excessive interruptions in compressions: Minimize pauses for procedures
  4. Inadequate compression depth or rate: Ensure proper technique
  5. Hyperventilation: Avoid excessive ventilation which can impede venous return
  6. Delayed defibrillation: Apply AED/defibrillator as soon as available
  7. Delayed epinephrine administration: For non-shockable rhythms, give as soon as feasible

By following these guidelines, providers can optimize the chances of survival with good neurological outcomes for cardiac arrest victims.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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