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Last updated: July 17, 2025View editorial policy

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Differential Diagnosis for Heel Pain

  • Single most likely diagnosis
    • Plantar fasciitis: This is the most common cause of heel pain, resulting from inflammation of the plantar fascia, a band of tissue that runs along the bottom of the foot. It is often associated with overuse, poor foot mechanics, or inadequate footwear.
  • Other Likely diagnoses
    • Achilles tendinitis: Inflammation of the Achilles tendon, which connects the calf muscles to the heel bone, can cause heel pain, especially with activities that involve running or jumping.
    • Heel spur: A bony growth on the underside of the heel bone, which can cause pain when walking or standing.
    • Bursitis: Inflammation of the fluid-filled sacs (bursae) that cushion the joints and reduce friction between bone and soft tissue can lead to heel pain.
    • Fat pad atrophy: Thinning of the fat pad under the heel can cause pain, especially in older adults.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Osteomyelitis: A bone infection that can cause severe heel pain, redness, and swelling. It requires prompt antibiotic treatment to prevent serious complications.
    • Tumor: Although rare, a tumor in the heel can cause persistent pain and should be considered in the differential diagnosis to ensure timely treatment.
    • Fracture: A stress fracture or other type of fracture in the heel can cause severe pain and requires proper diagnosis and treatment to prevent further complications.
  • Rare diagnoses
    • Rheumatoid arthritis: Although more commonly associated with other joints, rheumatoid arthritis can cause heel pain due to inflammation of the joints in the foot.
    • Gout: A form of arthritis characterized by sudden, severe attacks of pain, swelling, redness, and tenderness, which can occur in the heel.
    • Nerve entrapment: Compression or irritation of the nerves in the foot can cause heel pain, numbness, or tingling.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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