What are the alternatives to Anusol (hydrocortisone) suppositories for treating hemorrhoids when they are not covered by insurance?

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Last updated: July 17, 2025View editorial policy

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Alternatives to Anusol (Hydrocortisone) Suppositories for Hemorrhoids

For patients without insurance coverage for Anusol suppositories, several effective alternatives are available including dietary modifications, over-the-counter topical treatments, and office-based procedures depending on hemorrhoid severity.

First-Line Alternatives

Dietary and Lifestyle Modifications

  • Increase dietary fiber intake to approximately 30g/day through fruits, vegetables, whole grains, and legumes 1
  • Maintain adequate water intake to soften stools and ease bowel movements 1
  • Avoid straining during bowel movements by using relaxation techniques 1
  • Bulk-forming agents such as psyllium husk (Metamucil) or methylcellulose (Citrucel) 1
    • Psyllium has been shown in double-blind, placebo-controlled trials to reduce hemorrhoidal bleeding and painful defecation 1

Over-the-Counter Topical Treatments

  • Generic hydrocortisone creams (lower cost alternative to Anusol)
  • Topical analgesics for symptomatic relief of local pain and itching 1
  • Witch hazel pads for temporary relief of irritation and burning
  • Zinc oxide preparations to protect irritated skin

Treatment Algorithm Based on Hemorrhoid Classification

For First-Degree Hemorrhoids (bleeding without prolapse)

  1. Start with dietary fiber and adequate hydration 1
  2. Consider generic topical analgesics for symptomatic relief 1
  3. If symptoms persist: office-based sclerotherapy may be considered 1

For Second-Degree Hemorrhoids (prolapse that reduces spontaneously)

  1. Dietary modifications and bulk-forming agents 1
  2. Topical treatments for symptomatic relief
  3. If inadequate response: consider rubber band ligation (most effective office-based procedure with lowest recurrence rate) 1

For Third/Fourth-Degree Hemorrhoids

  1. Medical management first with dietary changes and topical treatments 1
  2. If symptoms persist: surgical referral may be necessary 1

Important Considerations

Cost-Effective Alternatives

  • Generic hydrocortisone creams are significantly less expensive than branded products
  • Bulk-forming agents like psyllium are cost-effective long-term solutions 1
  • Over-the-counter preparations without hydrocortisone (such as regular Anusol without hydrocortisone) may be less expensive

Cautions

  • Limit use of topical corticosteroids as long-term use of high-potency corticosteroid creams can be harmful 1
  • No data suggest that corticosteroid creams actually reduce hemorrhoidal swelling, bleeding, or protrusion - they primarily help with local inflammation 1

When to Seek Further Medical Evaluation

  • Persistent bleeding despite conservative measures
  • Severe pain unresponsive to topical treatments
  • Inability to reduce prolapsed hemorrhoids
  • Suspicion of other anorectal conditions

Additional Options

  • Nitroglycerin ointment has shown efficacy for pain relief in thrombosed external hemorrhoids in some studies 1
  • Flavonoids (such as diosmin/hesperidin combinations) may help relieve symptoms, though not FDA-approved in the US 1
  • Office-based procedures like rubber band ligation for persistent symptoms 1

Remember that the cornerstone of hemorrhoid management is addressing the underlying causes through dietary and lifestyle modifications, which are both effective and inexpensive alternatives to prescription medications.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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